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Protein

Glutaminase

Gene

glsA

Organism
Acaryochloris marina (strain MBIC 11017)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei63SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei158SubstrateUniRule annotation1
Binding sitei165SubstrateUniRule annotation1
Binding sitei189SubstrateUniRule annotation1
Binding sitei241SubstrateUniRule annotation1
Binding sitei259Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:AM1_0365
OrganismiAcaryochloris marina (strain MBIC 11017)
Taxonomic identifieri329726 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesAcaryochloridaceaeAcaryochloris
Proteomesi
  • UP000000268 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003360191 – 321GlutaminaseAdd BLAST321

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi329726.AM1_0365.

Structurei

3D structure databases

ProteinModelPortaliB0C9Y4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B0C9Y4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSELQVLLES FHQTYHQQDA GQLACYIPEL CKADPNWFAI SIVTTDGQTF
60 70 80 90 100
QVGNCQQTFT IQSISKVFVY GMALADHGQD ALLAKVGVEP TGDPFNSLIR
110 120 130 140 150
LDEDSKRPDN PMINAGAIAT TSLIRGNGPT DRLNRLLEMF RRYVGHEVFI
160 170 180 190 200
DMPVFMSERD TGHRNRAIAH LMLNFGMIDK NIDEALDLYF QQCSVLVNCH
210 220 230 240 250
DLAVMAATLA HKGINPITQE RAVESGYVKD ILSVMYTCGM YDFAGEWAYK
260 270 280 290 300
VGLPAKSGVS GGIMAVVPNR AGIAVFSPLL DEYGNSIRGR RVLEALSQKL
310 320
GLHLFDLSMG GCGLQAAMDS N
Length:321
Mass (Da):35,261
Last modified:February 26, 2008 - v1
Checksum:i675BA5367F209912
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000828 Genomic DNA. Translation: ABW25424.1.
RefSeqiWP_012161034.1. NC_009925.1.

Genome annotation databases

EnsemblBacteriaiABW25424; ABW25424; AM1_0365.
KEGGiamr:AM1_0365.
PATRICi20615290. VBIAcaMar40141_0298.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000828 Genomic DNA. Translation: ABW25424.1.
RefSeqiWP_012161034.1. NC_009925.1.

3D structure databases

ProteinModelPortaliB0C9Y4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi329726.AM1_0365.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABW25424; ABW25424; AM1_0365.
KEGGiamr:AM1_0365.
PATRICi20615290. VBIAcaMar40141_0298.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_ACAM1
AccessioniPrimary (citable) accession number: B0C9Y4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 26, 2008
Last modified: November 2, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.