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B0C967 (B0C967_ACAM1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123 EMBL ABW27748.1
Ordered Locus Names:AM1_2748
OrganismAcaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]
Taxonomic identifier329726 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length656 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5291 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6211N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
B0C967 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: EDE12273E6F6B3DD

FASTA65672,684
        10         20         30         40         50         60 
MSQPTIESIL QEQRLFPPPA DLAAQAEIKS AEEYEQLYAK AEADPQAFWA ELAEKELDWF 

        70         80         90        100        110        120 
EKWDTVLDWQ PPFAKWFVGG KLNITYNCLD RHLKTWRRNK AALIWEGEPG DSRTLTYAQL 

       130        140        150        160        170        180 
HREVCQTANV LKQLGVGKGD RVGIYMPMVP EAAIAMLACA RIGAPHTVVF GGFSAEALKD 

       190        200        210        220        230        240 
RLNDAEAKLV ITADGGFRKD KAVPLKTAVD KALADNGVPS VNNVLVVQRT KADVTMASNR 

       250        260        270        280        290        300 
DHWWHELVPA ASADCPPEPM DSEDMLFILY TSGTTGRPKG VVHTTGGYNL YTHMTCKWAF 

       310        320        330        340        350        360 
DLKDNDVYWC TADVGWITGH SYIVYGPLSN GATSLMYEGA PRPSNPGCFW DVVEKYGVNI 

       370        380        390        400        410        420 
FYTAPTAIRA FIKLGDQHPQ ARNLSSLRIL GTVGEPINPE AWIWYQQVIG GGKCPIIDTW 

       430        440        450        460        470        480 
WQTETGGFMI TPLPGATSTK PGSATRPFPG ILADVVDLDG NPVADNEGGY LVVRHPWPSM 

       490        500        510        520        530        540 
MRTVYGDDDR FRRTYWEHIP PKDGKYVYFA GDGVRRDEDG YFWIMGRVDD VINVSGHRLG 

       550        560        570        580        590        600 
TMEIESALVS HPAVAEAAVV GRPDDLKGED VFAFVTLENT HPPSDELNSE LKQHVVNEIG 

       610        620        630        640        650 
VIARPGEIRF ADALPKTRSG KIIRRFLRNL ASGEDIAGDA STMEDQSVLD KLRQGS

« Hide

References

[1]"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina."
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. expand/collapse author list , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000828 Genomic DNA. Translation: ABW27748.1.
RefSeqYP_001517064.1. NC_009925.1.

3D structure databases

ProteinModelPortalB0C967.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0C967.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5681556.
GenomeReviewsGene locus AM1_2748 in contig CP000828_GR.
KEGGamr:AM1_2748.
PATRIC20619786. VBIAcaMar40141_2524.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG547964.
OMAVISVSGH.
PhylomeDBB0C967.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0C967_ACAM1
AccessionPrimary (citable) accession number: B0C967
Entry history
Integrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info