ID   B0C4Z3_ACAM1            Unreviewed;       754 AA.
AC   B0C4Z3;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor {ECO:0000313|EMBL:ABW25105.1};
GN   OrderedLocusNames=AM1_0016 {ECO:0000313|EMBL:ABW25105.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Acaryochloridaceae; Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW25105.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW25105.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA   Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA   Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000828; ABW25105.1; -; Genomic_DNA.
DR   RefSeq; WP_012160727.1; NC_009925.1.
DR   AlphaFoldDB; B0C4Z3; -.
DR   STRING; 329726.AM1_0016; -.
DR   KEGG; amr:AM1_0016; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 543801at2; -.
DR   Proteomes; UP000000268; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268}.
FT   DOMAIN          5..128
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          168..241
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          243..295
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          328..461
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          470..726
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   MOD_RES         62
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   754 AA;  85582 MW;  E850B7E4C80C387D CRC64;
     MSKGTIICID DDRLILNTLR DQLQRIIDDS YEIEVAESGG EALELFTELE ADQIPIPLVI
     CDQNLPDMGG DSLLSYLQIQ YPKTRKILLT GEANLDAVIN AVNSANLYRY IAKPWDETDL
     GLTVKAALRS HLQDEQLIGQ NRTLRAMNAQ LQGEIDERQL VQQKLQESET RLESILNSLD
     DVVWSAAVEE FQLLYLNPAA EAVHGYPVSS FLSNPDLWLE VVHPADRHQM IHFFDQLLVA
     GSLNIEYRIL RPDGEIRWLK NRGHVITGDQ GRPHRLDGII YDITEQKRAQ AQLIHDAFHD
     ELTGLPNRNL MMERISQSLK RQHRTSDYQF ALLFIDLDRF KIINDSLGHI VGDQLLVAIA
     HLLENCVRTS DTVARLGGDE FTILLDGIQG IEDAIHVAER ILETLKSPFQ VGEHSVFTGS
     SIGIAYNSVQ YDDPTLLLRD ADIAMYRAKS LGKGCFVVFS PEMHAQTLSL LKLERDLRSA
     VDRQEFVLYY QPIIDLQSGD LTDVEVLVRW QHPDRGLVMP SEFIPLAEET GLIVEIGQWV
     LQEACQTLRD YQQQFASATE LKFSVNLSSE QLQDPNFIQT VDRVLSQSGL DGRYLKLELT
     ESMLMSHEEK HIKTLQQLRD RSITISLDDF GTGYSSLSYL YRFPLDTLKI DQSFVSRMIS
     EPKDAEIVNT IISLARTLNM DVIAEGIETE EEVLHLKKLG CERGQGYWFS PPMSQEKLEE
     HLQAGPQWFV QQQPMNPNFS FLAPSTSPIV DVQN
//