Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B0C4B4

- NU4C_ACAM1

UniProt

B0C4B4 - NU4C_ACAM1

Protein

NAD(P)H-quinone oxidoreductase chain 4

Gene

ndhD

Organism
Acaryochloris marina (strain MBIC 11017)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (26 Feb 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

    Catalytic activityi

    NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol.UniRule annotation

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
    2. quinone binding Source: UniProtKB-KW

    GO - Biological processi

    1. mitochondrial electron transport, NADH to ubiquinone Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD, NADP, Plastoquinone

    Enzyme and pathway databases

    BioCyciAMAR329726:GCZJ-2486-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NAD(P)H-quinone oxidoreductase chain 4UniRule annotation (EC:1.6.5.-UniRule annotation)
    Alternative name(s):
    NAD(P)H dehydrogenase I, chain 4UniRule annotation
    NDH-1, chain 4UniRule annotation
    Gene namesi
    Name:ndhDUniRule annotation
    Ordered Locus Names:AM1_2497
    OrganismiAcaryochloris marina (strain MBIC 11017)
    Taxonomic identifieri329726 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesAcaryochloris
    ProteomesiUP000000268: Chromosome

    Subcellular locationi

    Cellular thylakoid membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. thylakoid membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Thylakoid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 534534NAD(P)H-quinone oxidoreductase chain 4PRO_0000343228Add
    BLAST

    Keywords - PTMi

    Quinone

    Interactioni

    Protein-protein interaction databases

    STRINGi329726.AM1_2497.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei6 – 2621HelicalUniRule annotationAdd
    BLAST
    Transmembranei38 – 5821HelicalUniRule annotationAdd
    BLAST
    Transmembranei91 – 11121HelicalUniRule annotationAdd
    BLAST
    Transmembranei117 – 13721HelicalUniRule annotationAdd
    BLAST
    Transmembranei138 – 15821HelicalUniRule annotationAdd
    BLAST
    Transmembranei171 – 19121HelicalUniRule annotationAdd
    BLAST
    Transmembranei214 – 23421HelicalUniRule annotationAdd
    BLAST
    Transmembranei245 – 26521HelicalUniRule annotationAdd
    BLAST
    Transmembranei279 – 29921HelicalUniRule annotationAdd
    BLAST
    Transmembranei316 – 33621HelicalUniRule annotationAdd
    BLAST
    Transmembranei337 – 35721HelicalUniRule annotationAdd
    BLAST
    Transmembranei377 – 39923HelicalUniRule annotationAdd
    BLAST
    Transmembranei419 – 43921HelicalUniRule annotationAdd
    BLAST
    Transmembranei466 – 48621HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I subunit 4 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1008.
    HOGENOMiHOG000100683.
    KOiK05575.
    OMAiFFMVGAT.
    OrthoDBiEOG647TZ6.

    Family and domain databases

    HAMAPiMF_00491. NDH1_NuoM.
    InterProiIPR022997. NADH_Q_OxRdtase_chain4.
    IPR010227. NADH_Q_OxRdtase_chainM/4.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    IPR003918. NADH_UbQ_OxRdtase.
    IPR000260. NADH_UbQ_OxRdtase_chain4_N.
    [Graphical view]
    PfamiPF00361. Oxidored_q1. 1 hit.
    PF01059. Oxidored_q5_N. 1 hit.
    [Graphical view]
    PRINTSiPR01437. NUOXDRDTASE4.
    TIGRFAMsiTIGR01972. NDH_I_M. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B0C4B4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNPDTFPWLS TLIFFPIMAT VALPFIPDPK GKGDPIRWYA LVIGLIDFVL    50
    LIYAFYTQYD FAESGLQMVE HYDWLPQLGV QWSVGADGLS MPLILLTGFI 100
    TSLAILASWP VTYKPRLFYF LILAMYGGQI AVFAVQDLLV FFLVWELELV 150
    PVYLLLSIWG GYKRLYAATK FILYTAISSL FILVAALAMA FFGPDLTFDL 200
    QSLAAKDYPL TFQLLCYTGF LVAFAVKLPI VPLHTWLPDA HGEATAPVHM 250
    LLAGILLKMG GYALIRMNVE LLPDAHAYFA PALIILGVVN IIYAALTSFA 300
    QRNLKRKIAY SSISHMGFVL IGIASFTDLG MSGAVLQMVS HGLIGASLFF 350
    LVGATYDRTH TLILEEMGGV AQNMPKIFAM FTTCSMASLA LPGMSGFVAE 400
    LMVFVGLATS DAYSLAFRVP VVILAGIGVI LTPIYLLSML REIFYGPENK 450
    ELTSHEKLVD AEPREIFVIA CLLVPIIGIG LYPKIITQIY DAKTTQLVAY 500
    IRPSVPSIAM REAATVASVS DIEMDSSYQA PAIK 534
    Length:534
    Mass (Da):58,668
    Last modified:February 26, 2008 - v1
    Checksum:iEAA6AEA11E9F436F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000828 Genomic DNA. Translation: ABW27505.1.
    RefSeqiYP_001516819.1. NC_009925.1.

    Genome annotation databases

    EnsemblBacteriaiABW27505; ABW27505; AM1_2497.
    GeneIDi5681309.
    KEGGiamr:AM1_2497.
    PATRICi20619304. VBIAcaMar40141_2285.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000828 Genomic DNA. Translation: ABW27505.1 .
    RefSeqi YP_001516819.1. NC_009925.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 329726.AM1_2497.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABW27505 ; ABW27505 ; AM1_2497 .
    GeneIDi 5681309.
    KEGGi amr:AM1_2497.
    PATRICi 20619304. VBIAcaMar40141_2285.

    Phylogenomic databases

    eggNOGi COG1008.
    HOGENOMi HOG000100683.
    KOi K05575.
    OMAi FFMVGAT.
    OrthoDBi EOG647TZ6.

    Enzyme and pathway databases

    BioCyci AMAR329726:GCZJ-2486-MONOMER.

    Family and domain databases

    HAMAPi MF_00491. NDH1_NuoM.
    InterProi IPR022997. NADH_Q_OxRdtase_chain4.
    IPR010227. NADH_Q_OxRdtase_chainM/4.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    IPR003918. NADH_UbQ_OxRdtase.
    IPR000260. NADH_UbQ_OxRdtase_chain4_N.
    [Graphical view ]
    Pfami PF00361. Oxidored_q1. 1 hit.
    PF01059. Oxidored_q5_N. 1 hit.
    [Graphical view ]
    PRINTSi PR01437. NUOXDRDTASE4.
    TIGRFAMsi TIGR01972. NDH_I_M. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MBIC 11017.

    Entry informationi

    Entry nameiNU4C_ACAM1
    AccessioniPrimary (citable) accession number: B0C4B4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 2008
    Last sequence update: February 26, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3