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B0C312 (DAPF_ACAM1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:AM1_2349
OrganismAcaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]
Taxonomic identifier329726 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Diaminopimelate epimerase HAMAP MF_00197
PRO_1000077687

Sites

Active site751 By similarity
Active site2251 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0C312 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 33E9B96A9A211B28

FASTA28330,692
        10         20         30         40         50         60 
MRVEFTKYQG LGNDFILIDN RHQAQPCLTP DQAVQMCDRN FGIGGDGVIF ALPPEGDTDY 

        70         80         90        100        110        120 
TMRIYNSDGS EPEMCGNGIR CLARFLAHLE GKPLQTDITY RIHTLAGTIT PSLQADGLVK 

       130        140        150        160        170        180 
VDMGPPFLVP QEIPTTLGEG TDPVVNQPLE VAGQSWPVTC VSMGNPHCIT FVDDLEAIDF 

       190        200        210        220        230        240 
QTLGPQFEHH PVFPQRINTE FIQVIRPDYL KMLVWERGAG PTLACGTGAC AVLVAGVLTG 

       250        260        270        280 
KSQSQATIEL PGGPLQIRWA GEGQSVFMTG PAEKVFTGIY ETG

« Hide

References

[1]"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina."
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. expand/collapse author list , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MBIC 11017.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000828 Genomic DNA. Translation: ABW27359.1.
RefSeqYP_001516673.1. NC_009925.1.

3D structure databases

ProteinModelPortalB0C312.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0C312.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5681162.
GenomeReviewsGene locus AM1_2349 in contig CP000828_GR.
KEGGamr:AM1_2349.
PATRIC20619022. VBIAcaMar40141_2144.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG399442.
OMAFMTGPAT.
PhylomeDBB0C312.
ProtClustDBPRK00450.

Enzyme and pathway databases

BioCycAMAR329726:AM1_2349-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_ACAM1
AccessionPrimary (citable) accession number: B0C312
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 26, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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