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B0C1T8 (UPPP_ACAM1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:AM1_1064
OrganismAcaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]
Taxonomic identifier329726 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesAcaryochloris

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000083972

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane113 – 13321Helical; Potential
Transmembrane145 – 16521Helical; Potential
Transmembrane188 – 20821Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
B0C1T8 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 5A487CB07B7F9F79

FASTA26628,929
        10         20         30         40         50         60 
MTLLQAIILG IVQGLTEFLP VSSSGHLVLA SYYLGWWEKL PLYVDIATNT GTFFAVLVVL 

        70         80         90        100        110        120 
RKDVWQALSG FFAGLTSSTA RQQEGWRMAL LVVLGSIPTA MIGLGLKPIF EELNQPLYVS 

       130        140        150        160        170        180 
FALIVTGLVL WFTPKSGLKR NAMSLSWLDA TIGGIAQGCA VIPGISRSGS TISTMLWRGA 

       190        200        210        220        230        240 
TSDLAPRFSF LMYLVVSFGV AILGIDEVRE EGLQLAPLLG MIIASFVTGY IALLWLFSVL 

       250        260 
KKGQFKWFAP YLWVVAAITL IKVAMG 

« Hide

References

[1]"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina."
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. expand/collapse author list , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MBIC 11017.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000828 Genomic DNA. Translation: ABW26104.1.
RefSeqYP_001515418.1. NC_009925.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING329726.AM1_1064.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABW26104; ABW26104; AM1_1064.
GeneID5679889.
KEGGamr:AM1_1064.
PATRIC20616584. VBIAcaMar40141_0940.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycAMAR329726:GCZJ-1054-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_ACAM1
AccessionPrimary (citable) accession number: B0C1T8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 26, 2008
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families