Reviewed, UniProtKB/Swiss-Prot B0C132 (GLMM_ACAM1)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	AM1_3435

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Acaryochloris

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 455	455	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000343583
Sites
	Active site	106	1	Phosphoserine intermediate By similarity
	Metal binding	106	1	Magnesium; via phosphate group By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
Amino acid modifications
	Modified residue	106	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0C132-1 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: F37595567FAD8AD8	FASTA	455	49,461
	10 20 30 40 50 60 MAAAKDVNLF GTDGIRGHVG QHLTPQLALQ VGFCAGLELG QDASPHQPFI LGQDSRNSSD 70 80 90 100 110 120 MLAMALSAGL TAAGLDVWHI GLCPTPTVAY LTHHTEAVGG VMVSASHNPP ADNGIKFFQA 130 140 150 160 170 180 NGTKLPPTTQ GKIEQRIRAY SQQQPSGTWG HHFHRPELTK SYTDAIQTPL HAQVDFQGLK 190 200 210 220 230 240 VVLDLAWGAA TQLAPAVFKA MGAEVICLHD QPDGDRINVN CGSTHLAPLK AAVNLHEADV 250 260 270 280 290 300 GFAFDGDADR VLAIDCQGRT VDGDYILYLW GKALQQQNQL PKDLIVATVM SNLGFELAWQ 310 320 330 340 350 360 QQGGTLLRAA VGDQNVHAEM LNHGSMLGGE QSGHILCPHY GVSGDGLLTA LHLATIICQN 370 380 390 400 410 420 KTRLSCLVDD SFQTYPQLLK NVRVEDRDRR RNWQECQPLQ TLIDQATDDM GDQGRILVRA 430 440 450 SGTEPLIRVM VEARDMRMVN HWTDQLVRAV ETHLA

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000828 Genomic DNA. Translation: ABW28430.1.
RefSeq	YP_001517746.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5682244.
GenomeReviews	Gene locus AM1_3435 in contig CP000828_GR.
KEGG	amr:AM1_3435.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACAM1

Accession

Primary (citable) accession number: B0C132

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	February 26, 2008
Last modified:	November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)