B0C0D0 (B0C0D0_ACAM1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
EC=2.4.1.227 HAMAP MF_00033

Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase HAMAP MF_00033

Gene names

Name:	murG HAMAP MF_00033 EMBL ABW29622.1
Ordered Locus Names:	AM1_4648

Organism

Acaryochloris marina (strain MBIC 11017) [Complete proteome] [HAMAP]

Taxonomic identifier

329726 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Acaryochloris

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033
Catalytic activity	UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00033.
Sequence similarities	Belongs to the glycosyltransferase 28 family. MurG subfamily. HAMAP MF_00033

Ontologies

Keywords
Biological process	Cell cycle Cell division HAMAP MF_00033 Cell shape Cell wall biogenesis/degradation HAMAP MF_00033 Peptidoglycan synthesis HAMAP MF_00033
Cellular component	Cell inner membrane HAMAP MF_00033 Cell membrane Membrane
Molecular function	Glycosyltransferase HAMAP MF_00033 EMBL ABW29622.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	UDP-N-acetylgalactosamine biosynthetic process Inferred from electronic annotation. Source: InterPro cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW lipid glycosylation Inferred from electronic annotation. Source: HAMAP peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0C0D0 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 677870A6E87B8D26	FASTA	366	39,428
	10 20 30 40 50 60 MSNSESVAIT EQPQRFLIAA SGTGGHLFPA LAVAEVLEAE QFQLEWLGVS NRLETQLVPK 70 80 90 100 110 120 KYPLRTVPIE GLQTRIGPKT PILLGKLAVA VWQTRQLLKR GQFKGVLTTG GYIAAPAILA 130 140 150 160 170 180 AWSLGLPRVI HESNAIPGKV TRWLSSICTG VGLGLEDATT YLPKDKTVVV GTPVRPAFLT 190 200 210 220 230 240 PCELDLPIPP EATLIVVAGG SQGAVSVNKL VRACAPAWLE TGAWIVHLTG AQDPDAQSFQ 250 260 270 280 290 300 HPHYLSMPFY DNMAGLLQRA NLAISRAGAG TLSELAIAST PALLIPYPYA AEDHQAFNAA 310 320 330 340 350 360 AFVKAGAAEM YRQDELTEEQ LKQTVLQWIQ EPQVLEEMAV KAYSLAVPNS TERFAQLILE QIEASP

References

[1]

"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina." Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L. , Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W. Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008) [PubMed: 18252824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000828 Genomic DNA. Translation: ABW29622.1.
RefSeq	YP_001518940.1. NC_009925.1.
3D structure databases
ProteinModelPortal	B0C0D0.
ModBase	Search...
Protein-protein interaction databases
STRING	B0C0D0.
Protein family/group databases
CAZy	GT28. Glycosyltransferase Family 28.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5683450.
GenomeReviews	Gene locus AM1_4648 in contig CP000828_GR.
KEGG	amr:AM1_4648.
PATRIC	20623372. VBIAcaMar40141_4304.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG617076.
OMA	EDHQTKN.
PhylomeDB	B0C0D0.
Family and domain databases
HAMAP	MF_00033. MurG. [Tree]
InterPro	IPR006009. GlcNAc_MurG. IPR004276. Glyco_trans_28. IPR007235. Glyco_trans_28_C. [Graphical view]
KO	K02563.
PANTHER	PTHR21015:SF22. PTHR21015:SF22. 1 hit.
Pfam	PF04101. Glyco_tran_28_C. 1 hit. PF03033. Glyco_transf_28. 1 hit. [Graphical view]
TIGRFAMs	TIGR01133. MurG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0C0D0_ACAM1

Accession

Primary (citable) accession number: B0C0D0

Entry history

Integrated into UniProtKB/TrEMBL:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)