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B0BWL0 (B0BWL0_RICRO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def2 HAMAP MF_00163
Ordered Locus Names:RrIowa_0336
OrganismRickettsia rickettsii (strain Iowa) [Complete proteome] [HAMAP]
Taxonomic identifier452659 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length175 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1421 By similarity HAMAP MF_00163
Metal binding991Iron By similarity HAMAP MF_00163
Metal binding1411Iron By similarity HAMAP MF_00163
Metal binding1451Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
B0BWL0 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 1A6B239D8ECDB573

FASTA17520,237
        10         20         30         40         50         60 
MSILPIVTAP DERLKQKSQP VLEFTDQTRK FMDDMLKTMY HEDGAGLAAV QVGVLKRILV 

        70         80         90        100        110        120 
IDIQDHDSVA RPKDFYPLFI VNPEVIEKAE ELVTANEGCI SLPEQRIEVA RPESIKIRYL 

       130        140        150        160        170 
DYHGKSQELK ANDWLARVIQ HEYDHLEGKL MIDYLSNLKR DVVLRKLKKL KNNIV

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References

[1]"Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa."
Ellison D.W., Clark T.R., Sturdevant D.E., Virtaneva K., Porcella S.F., Hackstadt T.
Infect. Immun. 76:542-550(2008) [PubMed: 18025092] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Iowa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000766 Genomic DNA. Translation: ABY72236.1.
RefSeqYP_001649642.1. NC_010263.2.

3D structure databases

ProteinModelPortalB0BWL0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0BWL0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5850110.
GenomeReviewsGene locus RrIowa_0336 in contig CP000766_GR.
KEGGrrj:RrIowa_0336.
PATRIC17906560. VBIRicRic59104_0332.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG665227.
OMAETMIASE.
ProtClustDBPRK00150.

Enzyme and pathway databases

BioCycRRIC452659:RRIOWA_0336-MONOMER.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB0BWL0_RICRO
AccessionPrimary (citable) accession number: B0BWL0
Entry history
Integrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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