B0BW16 (DGTL1_RICRO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Gene names

Ordered Locus Names:

RrIowa_0122

Organism

Rickettsia rickettsii (strain Iowa) [Complete proteome] [HAMAP]

Taxonomic identifier

452659 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 384	384	Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP MF_01212		PRO_1000085572

Sequences

	Sequence		Length	Mass (Da)
	B0BW16 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 6899E68F48E9A84D	FASTA	384	44,284
	10 20 30 40 50 60 MLASYASDPL KSRGRLYKEI PTSYRNEFER DRDRIIHTNA FRRLQYKTQV FINHEGDHYR 70 80 90 100 110 120 NRLTHSLEVS TVARSVASTL NLSNDLAETI ALAHDLGHTP FGHAGERALN ECMREYNGFS 130 140 150 160 170 180 HNAQSLKILT LLEKRYAAYN GVNLTWEVLE GIVKHNGPIL GEINEYIAEY NKQNDLELST 190 200 210 220 230 240 YASAEAQIAA LADDISYISH DLEDSIGAKI IDFNSLAELK YIDQHVVELK SKFKNISSSC 250 260 270 280 290 300 LIYEVVRKLI HELITDLLWQ TKENLNKEKI TNIDEIRNLN YQIVDFTEKT NKNIKETKKF 310 320 330 340 350 360 LHERVYKSNK ITAISLKCTK IVQGLFKVYM DDINLLPVNW KMLIDSNETY SKARVIADYI 370 380 AGMTDRFAIQ EYNQLCSTSY ITCF

References

[1]

"Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa." Ellison D.W., Clark T.R., Sturdevant D.E., Virtaneva K., Porcella S.F., Hackstadt T. Infect. Immun. 76:542-550(2008) [PubMed: 18025092] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Iowa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000766 Genomic DNA. Translation: ABY72042.1.
RefSeq	YP_001649448.1. NC_010263.2.
3D structure databases
ProteinModelPortal	B0BW16.
ModBase	Search...
Protein-protein interaction databases
STRING	B0BW16.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5849826.
GenomeReviews	Gene locus RrIowa_0122 in contig CP000766_GR.
KEGG	rrj:RrIowa_0122.
PATRIC	17906136. VBIRicRic59104_0124.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG500914.
OMA	ITRFVED.
ProtClustDB	PRK01286.
Enzyme and pathway databases
BioCyc	RRIC452659:RRIOWA_0122-MONOMER.
Family and domain databases
HAMAP	MF_01212. dGTPase_type2. [Tree]
InterPro	IPR006261. dGTP_triP_hydro. IPR023293. dGTP_triP_hydro_central. IPR023023. dGTP_triP_hydro_type2. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. [Graphical view]
Gene3D	G3DSA:1.10.3410.10. G3DSA:1.10.3410.10. 1 hit. G3DSA:1.10.3210.10. HD. 1 hit.
KO	K01129.
Pfam	PF01966. HD. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. DGTP_triPase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DGTL1_RICRO

Accession

Primary (citable) accession number: B0BW16

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program