UniProtKB - B0BUR8 (B0BUR8_RICRO)
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Protein
Cell division protein FtsZ
Gene
ftsZ
Organism
Rickettsia rickettsii (strain Iowa)
Status
Functioni
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 142 | GTPUniRule annotation | 1 | |
Binding sitei | 146 | GTPUniRule annotation | 1 | |
Binding sitei | 190 | GTPUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 24 – 28 | GTPUniRule annotation | 5 | |
Nucleotide bindingi | 111 – 113 | GTPUniRule annotation | 3 |
GO - Molecular functioni
- GTPase activity Source: UniProtKB-UniRule
- GTP binding Source: UniProtKB-UniRule
GO - Biological processi
- cell septum assembly Source: UniProtKB-UniRule
- FtsZ-dependent cytokinesis Source: UniProtKB-UniRule
- protein polymerization Source: UniProtKB-UniRule
Keywordsi
Biological process | Cell cycle, Cell division, SeptationUniRule annotation |
Ligand | GTP-bindingUniRule annotation, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | RRIC452659:G1G9G-1167-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division protein FtsZUniRule annotation |
Gene namesi | Name:ftsZUniRule annotationImported Ordered Locus Names:RrIowa_1207Imported |
Organismi | Rickettsia rickettsii (strain Iowa)Imported |
Taxonomic identifieri | 452659 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
- cell division site Source: UniProtKB-UniRule
- cytoplasm Source: UniProtKB-UniRule
Keywords - Cellular componenti
CytoplasmUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 208 | TubulinInterPro annotationAdd BLAST | 193 | |
Domaini | 210 – 329 | Tubulin_CInterPro annotationAdd BLAST | 120 |
Sequence similaritiesi
Belongs to the FtsZ family.UniRule annotation
Phylogenomic databases
HOGENOMi | HOG000049094. |
KOi | K03531. |
OMAi | MRAVKGI. |
OrthoDBi | POG091H02KK. |
Family and domain databases
CDDi | cd02201. FtsZ_type1. 1 hit. |
Gene3Di | 3.30.1330.20. 1 hit. 3.40.50.1440. 1 hit. |
HAMAPi | MF_00909. FtsZ. 1 hit. |
InterProi | View protein in InterPro IPR000158. Cell_div_FtsZ. IPR020805. Cell_div_FtsZ_CS. IPR024757. FtsZ_C. IPR008280. Tub_FtsZ_C. IPR018316. Tubulin/FtsZ_2-layer-sand-dom. IPR037103. Tubulin/FtsZ_C_sf. IPR036525. Tubulin/FtsZ_GTPase_sf. IPR003008. Tubulin_FtsZ_GTPase. |
Pfami | View protein in Pfam PF12327. FtsZ_C. 1 hit. PF00091. Tubulin. 1 hit. |
PRINTSi | PR00423. CELLDVISFTSZ. |
SMARTi | View protein in SMART SM00864. Tubulin. 1 hit. SM00865. Tubulin_C. 1 hit. |
SUPFAMi | SSF52490. SSF52490. 1 hit. SSF55307. SSF55307. 1 hit. |
TIGRFAMsi | TIGR00065. ftsZ. 1 hit. |
PROSITEi | View protein in PROSITE PS01134. FTSZ_1. 1 hit. PS01135. FTSZ_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
B0BUR8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVLNIKAPEN IVLKPTITVF GVGGAGSNAV NNMISANLQG ANFVVANTDA
60 70 80 90 100
QSLEHSLCTN KIQLGVSTTR GLGAGASPEV GALAAQESES EIRNYLENSN
110 120 130 140 150
MVFITAGMGG GTGTGSAPVI ARIAKELGIL TVGVATKPFH FEGGHRMKTA
160 170 180 190 200
DKGLIELQQF VDTLIVIPNQ NLFRIANEQT TFADAFKMAD DVLHAGVRGV
210 220 230 240 250
TDLMIMPGLI NLDFADIKAV MSEMGKAMMG TGEASGEDRA IKAAESAISN
260 270 280 290 300
PLLDHSSMCG ARGVLINITG GSDMTLFEVD NAANRIREEV DNLDANIIFG
310 320 330 340 350
STFNPELKGM IRVSVVATGI DADKVPTYKP AIAETTNIVP EETYNKAIAQ
360 370 380 390 400
PTQIEEMPDF NSYSTKNIEI TDSPINQNLI GNEKELGLHA NTFNKSEDDS
410 420 430 440 450
PKPSFLGKIW GSLRASNNQT LERKNVVVST LDQDNKESDI HDIPAFLRKQ
RD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000766 Genomic DNA. Translation: ABY72978.1. |
RefSeqi | WP_012262534.1. NC_010263.3. |
Genome annotation databases
EnsemblBacteriai | ABY72978; ABY72978; RrIowa_1207. |
KEGGi | rrj:RrIowa_1207. |
Similar proteinsi
Entry informationi
Entry namei | B0BUR8_RICRO | |
Accessioni | B0BUR8Primary (citable) accession number: B0BUR8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 26, 2008 |
Last sequence update: | February 26, 2008 | |
Last modified: | March 28, 2018 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |