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B0BUJ2

- RNPA_RICRO

UniProt

B0BUJ2 - RNPA_RICRO

Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Rickettsia rickettsii (strain Iowa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. tRNA binding Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciRRIC452659:GHSN-1041-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P proteinUniRule annotation
    Short name:
    RNaseP proteinUniRule annotation
    Alternative name(s):
    Protein C5UniRule annotation
    Gene namesi
    Name:rnpAUniRule annotation
    Ordered Locus Names:RrIowa_1112
    OrganismiRickettsia rickettsii (strain Iowa)
    Taxonomic identifieri452659 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000796: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 118118Ribonuclease P protein componentPRO_1000100383Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi452659.RrIowa_1112.

    Structurei

    3D structure databases

    ProteinModelPortaliB0BUJ2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RnpA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0594.
    HOGENOMiHOG000010878.
    KOiK03536.
    OMAiFHERYFI.
    OrthoDBiEOG654P5P.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    HAMAPiMF_00227. RNase_P.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view]
    PfamiPF00825. Ribonuclease_P. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR00188. rnpA. 1 hit.
    PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0BUJ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSITSLKNQK EFELINKLGK KLHERYFILV IATKLPKIFL ESKYNTFLGI    50
    KVSRKLNKKA VVRNKIKRRI RHLIRIIVSD SSFKDIKFAM IIIPRKGFEE 100
    INFSHLNYEL SKLILRNI 118
    Length:118
    Mass (Da):14,029
    Last modified:February 26, 2008 - v1
    Checksum:iC2E86D6A43BE146B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000766 Genomic DNA. Translation: ABY72902.1.
    RefSeqiYP_001650308.1. NC_010263.2.

    Genome annotation databases

    EnsemblBacteriaiABY72902; ABY72902; RrIowa_1112.
    GeneIDi5849378.
    KEGGirrj:RrIowa_1112.
    PATRICi17908125. VBIRicRic59104_1096.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000766 Genomic DNA. Translation: ABY72902.1 .
    RefSeqi YP_001650308.1. NC_010263.2.

    3D structure databases

    ProteinModelPortali B0BUJ2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 452659.RrIowa_1112.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABY72902 ; ABY72902 ; RrIowa_1112 .
    GeneIDi 5849378.
    KEGGi rrj:RrIowa_1112.
    PATRICi 17908125. VBIRicRic59104_1096.

    Phylogenomic databases

    eggNOGi COG0594.
    HOGENOMi HOG000010878.
    KOi K03536.
    OMAi FHERYFI.
    OrthoDBi EOG654P5P.

    Enzyme and pathway databases

    BioCyci RRIC452659:GHSN-1041-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    HAMAPi MF_00227. RNase_P.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view ]
    Pfami PF00825. Ribonuclease_P. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR00188. rnpA. 1 hit.
    PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa."
      Ellison D.W., Clark T.R., Sturdevant D.E., Virtaneva K., Porcella S.F., Hackstadt T.
      Infect. Immun. 76:542-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Iowa.

    Entry informationi

    Entry nameiRNPA_RICRO
    AccessioniPrimary (citable) accession number: B0BUJ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: February 26, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3