B0BTN3 (GLPB_ACTPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Short name=Anaerobic G-3-P dehydrogenase subunit B
Short name=Anaerobic G3Pdhase B
EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	APJL_0399

Organism

Actinobacillus pleuropneumoniae serotype 3 (strain JL03) [Complete proteome] [HAMAP]

Taxonomic identifier

434271 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus › Actinobacillus pleuropneumoniae › Actinobacillus pleuropneumoniae serovar 3

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity. HAMAP-Rule MF_00753
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP-Rule MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP-Rule MF_00753
Subunit structure	Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycerol catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 428	428	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP-Rule MF_00753		PRO_1000133354

Sequences

	Sequence		Length	Mass (Da)
	B0BTN3 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 6602C65C34B60043	FASTA	428	46,784
	10 20 30 40 50 60 MNFDVVIIGG GLAGLTCGIA LQEQGKRCVI INNGQAAIDF SSGSMDLLSR LPSGQKVENV 70 80 90 100 110 120 YQSLDELKLQ APEHPYSILG KDQVLAKAQQ FEQLAQSLNL HLEGSTVQNH ERITPLGGLR 130 140 150 160 170 180 ATWLSPNSVP TVKHLTALAD KQVAILGIEG YHDFQPQLLA DNLKQHSQFA DYEFTIGYLN 190 200 210 220 230 240 IPELDYLRQN SREFRSVNIA QLLEHKLSFQ DLVQEIKQAA GNAKAVFLPA CFGLDNQDFF 250 260 270 280 290 300 NSLQQATGLA LFELPTLPPS LLGIRQHRQL RSRFEQLGGM MMNGDRAVKA EFEGKNVARI 310 320 330 340 350 360 FTTSHQEEPI SADYFVLAAG SFFSNGLVAE FERVKEPVFD LDICGCKNFD SSDRFTWTNN 370 380 390 400 410 420 RFAAPQPYQS AGVVINSACQ VQKNGEVVSN LYAVGNVIGG FQGIEQGCGS GVAVVTALTV AEQIGGTK

References

[1]

"Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China." Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W., Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T. , Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S., Zhao G.-P., Chen H. PLoS ONE 3:E1450-E1450(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JL03.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000687 Genomic DNA. Translation: ABY68988.1.
RefSeq	YP_001651432.1. NC_010278.1.
3D structure databases
ProteinModelPortal	B0BTN3.
ModBase	Search...
Protein-protein interaction databases
STRING	434271.APJL_0399.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABY68988; ABY68988; APJL_0399.
GeneID	5851892.
KEGG	apj:APJL_0399.
PATRIC	20750025. VBIActPle136345_0401.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3075.
HOGENOM	HOG000278489.
KO	K00112.
OMA	FRSVNIS.
ProtClustDB	PRK05329.
Enzyme and pathway databases
BioCyc	APLE434271:GIX7-402-MONOMER.
UniPathway	UPA00618; UER00673.
Family and domain databases
HAMAP	MF_00753. Glycerol3P_GlpB.
InterPro	IPR003953. FAD_bind_dom. IPR009158. G3P_DH_GlpB_su. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_ACTPJ

Accession

Primary (citable) accession number: B0BTN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 26, 2008
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program