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Protein

Xylose isomerase

Gene

xylA

Organism
Actinobacillus pleuropneumoniae serotype 3 (strain JL03)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei101UniRule annotation1
Active sitei104UniRule annotation1
Metal bindingi232Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 1UniRule annotation1
Metal bindingi268Magnesium 2UniRule annotation1
Metal bindingi271Magnesium 2UniRule annotation1
Metal bindingi296Magnesium 1UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi339Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:APJL_1955
OrganismiActinobacillus pleuropneumoniae serotype 3 (strain JL03)
Taxonomic identifieri434271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus
Proteomesi
  • UP000008547 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002002721 – 439Xylose isomeraseAdd BLAST439

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0BTI9
SMRiB0BTI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

B0BTI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNYFDKIEK VKYEGADSTN PFAFKHYNPN EVILGKTMAE HLRLAVCYWH
60 70 80 90 100
TFCWTGNDMF GVGSLDRSWQ KTGDLLEGAK QKAEIAFEFF QKLGIPYYCF
110 120 130 140 150
HDVDIAPEGN SYKEYVHNFH TMVDILEKKQ AETGVKLLWG TANCFTNPRY
160 170 180 190 200
MSGASTNPNP EVFSWAASQV FNAMNATKRL GGENYVLWGG REGYETLLNT
210 220 230 240 250
DLKREREQIG RFMQMVVEHK HKIGFNGTLL IEPKPQEPTK HQYDYDVATV
260 270 280 290 300
YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATAAALD IFGSIDANRG
310 320 330 340 350
DPQLGWDTDQ FPNSVEENTL VMYEILKAGG FTTGGFNFDA KIRRQSTDPY
360 370 380 390 400
DLFHGHIGAI DVLALSLKRA AKMIEDKTLQ GIVDQRYAGW NGDLGQQILA
410 420 430
GKASLEDLAK IVESKALDPK PVSGQQEYLE NLVNNYIYR
Length:439
Mass (Da):49,636
Last modified:February 26, 2008 - v1
Checksum:i93723DE3CF888C7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000687 Genomic DNA Translation: ABY70503.1
RefSeqiWP_005599638.1, NC_010278.1

Genome annotation databases

EnsemblBacteriaiABY70503; ABY70503; APJL_1955
GeneIDi4849662
KEGGiapj:APJL_1955

Similar proteinsi

Entry informationi

Entry nameiXYLA_ACTPJ
AccessioniPrimary (citable) accession number: B0BTI9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 26, 2008
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health