Reviewed, UniProtKB/Swiss-Prot B0BR01 (PSD_ACTPJ)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	APJL_1432

Organism

Actinobacillus pleuropneumoniae serotype 3 (strain JL03) [Complete proteome] [HAMAP]

Taxonomic identifier

434271 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00662
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000131330
	Chain	263 – 296	34	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000131331
Sites
	Site	262 – 263	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	263	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0BR01-1 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: E0B5079993FA36D5	FASTA	296	33,654
	10 20 30 40 50 60 MSLKPYATPT YWQRVKVAFQ YIFPQLPVTR LAGWLAEQKW GAVTHFIIRT FAKQYKVNLS 70 80 90 100 110 120 EAQKSNASDY ATFNEFFIRP LKENARPINQ DAQALCLPAD GKVSESGKIE DDRLLQAKGH 130 140 150 160 170 180 FFTLETLLAN DQEMANKFKD GHFITTYLSP RDYHRVHMPC DATLRKMIYV PGELFSVNPF 190 200 210 220 230 240 LAEHVPNLFA RNERVICEFE TEFGPMVQIL VGATITASMS TVWAGIINPP RTKEVVEYHY 250 260 270 280 290 ETSGETAVHL KKGQEMGAFR LGSTVINLFP KDSVEFEAHL QAGVETRMGE RLAKIK

References

[1]

"Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China." Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W., Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T. , Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S., Zhao G.-P., Chen H. PLoS ONE 3:E1450-E1450(2008) [PubMed: 18197260] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000687 Genomic DNA. Translation: ABY69986.1.
RefSeq	YP_001652430.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5851387.
GenomeReviews	Gene locus APJL_1432 in contig CP000687_GR.
KEGG	apj:APJL_1432.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG302256.
OMA	ALFSVNP.
Family and domain databases
HAMAP	MF_00662. PS_decarb_type1. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_ACTPJ

Accession

Primary (citable) accession number: B0BR01

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 26, 2008
Last modified:	February 9, 2010
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)