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B0BNS1 (ACKA_ACTPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:APJL_0636
OrganismActinobacillus pleuropneumoniae serotype 3 (strain JL03) [Complete proteome] [HAMAP]
Taxonomic identifier434271 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Actinobacillus

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Acetate kinase HAMAP MF_00020
PRO_1000089957

Sequences

Sequence LengthMass (Da)Tools
B0BNS1 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 619DA9544AEDECAB

FASTA40243,555
        10         20         30         40         50         60 
MSKNLILILN CGSSSLKFAV LDPKTGDEKL SGLAEAFNLE DARIKWKLHG EKGNADLGAG 

        70         80         90        100        110        120 
AAHSEALTFI ANELLSEELK SSIGAIGHRI VHGGEQFTSS VVINDDVVKG IEHAIQFAPL 

       130        140        150        160        170        180 
HNPAHLIGIK EAFRIFPELK EKNVAVFDTA FHQTMPEEAF LYALPYKLYK EHGIRRYGAH 

       190        200        210        220        230        240 
GTSHLFITSQ VAELAGKPVD QTNAIICHLG NGGSVSVVRN GKCIDTSMGL TPLEGLVMGT 

       250        260        270        280        290        300 
RSGDIDPAIV FYLYKNLGMS MEQIEDTLVK KSGLLGLTEV TSDCRYAEDN YEDASKPEAK 

       310        320        330        340        350        360 
RALDVYSYRL AKYIGAYMAI LGDDHLDAIA FTGGIGENSG HVRELALNHL KLFGVKLDVE 

       370        380        390        400 
RNLAARFGKS GVITADDSTF KAVVIPTNEE LVIAQDTAKL AL

« Hide

References

[1]"Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China."
Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W., Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T. expand/collapse author list , Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S., Zhao G.-P., Chen H.
PLoS ONE 3:E1450-E1450(2008) [PubMed: 18197260] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JL03.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000687 Genomic DNA. Translation: ABY69206.1.
RefSeqYP_001651650.1. NC_010278.1.

3D structure databases

ProteinModelPortalB0BNS1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0BNS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5852773.
GenomeReviewsGene locus APJL_0636 in contig CP000687_GR.
KEGGapj:APJL_0636.
PATRIC20750510. VBIActPle136345_0640.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAYLPEARI.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycAPLE434271:APJL_0636-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_ACTPJ
AccessionPrimary (citable) accession number: B0BNS1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 26, 2008
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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