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Protein

Peptidyl-prolyl cis-trans isomerase

Gene

Pin1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotation

Enzyme and pathway databases

BRENDAi5.2.1.8 5301
ReactomeiR-RNO-6804756 Regulation of TP53 Activity through Phosphorylation
R-RNO-6811555 PI5P Regulates TP53 Acetylation
R-RNO-936440 Negative regulators of DDX58/IFIH1 signaling

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Gene namesi
Name:Pin1Imported
Synonyms:LOC364561Imported, Pin1_predictedImported
ORF Names:rCG_31594Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1310299 Pin1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiB0BNL2

Expressioni

Gene expression databases

BgeeiENSRNOG00000020474

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027819

Structurei

3D structure databases

SMRiB0BNL2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 39WWInterPro annotationAdd BLAST35
Domaini54 – 165PpiCInterPro annotationAdd BLAST112

Phylogenomic databases

eggNOGiKOG3259 Eukaryota
COG0760 LUCA
GeneTreeiENSGT00640000091578
HOGENOMiHOG000275331
HOVERGENiHBG002101
KOiK09578
OMAiDEVQCLH
OrthoDBiEOG091G0RO7
TreeFamiTF101101

Family and domain databases

CDDicd00201 WW, 1 hit
InterProiView protein in InterPro
IPR000297 PPIase_PpiC
IPR023058 PPIase_PpiC_CS
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00639 Rotamase, 1 hit
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00456 WW, 1 hit
SUPFAMiSSF51045 SSF51045, 1 hit
PROSITEiView protein in PROSITE
PS01096 PPIC_PPIASE_1, 1 hit
PS50198 PPIC_PPIASE_2, 1 hit
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

B0BNL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEEKLPSG WEKRMSRSSG RVYYFNHITN ASQWERPSGG STVGGGSKNG
60 70 80 90 100
QGEPARVRCS HLLVKHSQSR RPSSWRQEKI TRSKEEALEL INGYIQKIKS
110 120 130 140 150
GEEDFESLAS QFSDCSSAKA RGDLGAFSRG QMQKPFEDAS FALRTGEMSG
160
PVFTDSGIHI ILRTE
Length:165
Mass (Da):18,332
Last modified:February 26, 2008 - v1
Checksum:iCFE809731FF0A518
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07069434 Genomic DNA No translation available.
BC158867 mRNA Translation: AAI58868.1
CH473993 Genomic DNA Translation: EDL78356.1
RefSeqiNP_001100171.1, NM_001106701.2
UniGeneiRn.6291

Genome annotation databases

EnsembliENSRNOT00000027818; ENSRNOP00000027819; ENSRNOG00000020474
GeneIDi298696
KEGGirno:298696

Similar proteinsi

Entry informationi

Entry nameiB0BNL2_RAT
AccessioniPrimary (citable) accession number: B0BNL2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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