SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0BNG0

- EMC2_RAT

UniProt

B0BNG0 - EMC2_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
ER membrane protein complex subunit 2
Gene
Emc2, Ttc35
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
ER membrane protein complex subunit 2
Alternative name(s):
Tetratricopeptide repeat protein 35
Short name:
TPR repeat protein 35
Gene namesi
Name:Emc2
Synonyms:Ttc35
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi1310430. Emc2.

Subcellular locationi

Nucleus By similarity. Cytoplasm By similarity

GO - Cellular componenti

  1. ER membrane protein complex Source: UniProtKB
  2. cytoplasm Source: UniProtKB
  3. endoplasmic reticulum Source: UniProtKB
  4. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 297296ER membrane protein complex subunit 2
PRO_0000333731Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiB0BNG0.
PRIDEiB0BNG0.

Expressioni

Gene expression databases

GenevestigatoriB0BNG0.

Interactioni

Subunit structurei

Component of the ER membrane protein complex (EMC) By similarity.

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006890.

Structurei

3D structure databases

ProteinModelPortaliB0BNG0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati87 – 12034TPR 1
Add
BLAST
Repeati155 – 18834TPR 2
Add
BLAST
Repeati192 – 22534TPR 3
Add
BLAST

Sequence similaritiesi

Belongs to the EMC2 family.
Contains 3 TPR repeats.

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiNOG236229.
HOGENOMiHOG000007547.
HOVERGENiHBG055231.
OrthoDBiEOG7QK0C9.
PhylomeDBiB0BNG0.
TreeFamiTF312997.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF00515. TPR_1. 1 hit.
[Graphical view]
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B0BNG0-1 [UniParc]FASTAAdd to Basket

« Hide

MAKVTERYDV TWEEMRDKMR KWREENSRNS EQIMEVGEEL INDYASKLGD    50
DIWIIYEQVM IAALDYGRDD LALFCLQELR RQFPGSHRVK RLTGMRFEAM 100
ERYDDAIQLY DRILQEDPTN TAARKRKIAI RKAQGKNVEA IRELNEYLEQ 150
FVGDQEAWHE LAELYINEHD YAKAAFCLEE LMMTNPHNHL YCQQYAEVKY 200
TQGGLENLEL SRKYFAQALK LNNRNMRALF GLYMSASHIA SNPKASAKMK 250
KDNIRYAGWA ANQINRAYQF AGRSKKETKS SLKAVEDMLE TLQITQS 297
Length:297
Mass (Da):34,870
Last modified:February 26, 2008 - v1
Checksum:i7B8ABD95D4B8A849
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC158805 mRNA. Translation: AAI58806.1.
RefSeqiNP_001107257.1. NM_001113785.1.
UniGeneiRn.203197.

Genome annotation databases

GeneIDi362905.
KEGGirno:362905.
UCSCiRGD:1310430. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC158805 mRNA. Translation: AAI58806.1 .
RefSeqi NP_001107257.1. NM_001113785.1.
UniGenei Rn.203197.

3D structure databases

ProteinModelPortali B0BNG0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000006890.

Proteomic databases

PaxDbi B0BNG0.
PRIDEi B0BNG0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 362905.
KEGGi rno:362905.
UCSCi RGD:1310430. rat.

Organism-specific databases

CTDi 9694.
RGDi 1310430. Emc2.

Phylogenomic databases

eggNOGi NOG236229.
HOGENOMi HOG000007547.
HOVERGENi HBG055231.
OrthoDBi EOG7QK0C9.
PhylomeDBi B0BNG0.
TreeFami TF312997.

Miscellaneous databases

NextBioi 681734.
PROi B0BNG0.

Gene expression databases

Genevestigatori B0BNG0.

Family and domain databases

Gene3Di 1.25.40.10. 2 hits.
InterProi IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view ]
Pfami PF00515. TPR_1. 1 hit.
[Graphical view ]
PROSITEi PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Liver.

Entry informationi

Entry nameiEMC2_RAT
AccessioniPrimary (citable) accession number: B0BNG0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 26, 2008
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi