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Protein
Submitted name:

HtrA serine peptidase 2

Gene

Htra2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • identical protein binding Source: Ensembl
  • serine-type endopeptidase activity Source: Ensembl
  • serine-type peptidase activity Source: RGD

GO - Biological processi

Protein family/group databases

MEROPSiS01.278.

Names & Taxonomyi

Protein namesi
Submitted name:
HtrA serine peptidase 2Imported
Submitted name:
RCG56292, isoform CRA_dImported
Gene namesi
Name:Htra2Imported
ORF Names:rCG_56292Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1308906. Htra2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei106 – 125HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000022448.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000030076.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini350 – 445PDZInterPro annotationAdd BLAST96

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1320. Eukaryota.
COG0265. LUCA.
GeneTreeiENSGT00510000046315.
HOGENOMiHOG000223641.
HOVERGENiHBG052044.
KOiK08669.
OMAiAHVVINK.
OrthoDBiEOG091G0LXR.
TreeFamiTF323480.

Family and domain databases

InterProiView protein in InterPro
IPR001478. PDZ.
IPR009003. Peptidase_S1_PA.
IPR001940. Peptidase_S1C.
PfamiView protein in Pfam
PF13180. PDZ_2. 1 hit.
PRINTSiPR00834. PROTEASES2C.
SMARTiView protein in SMART
SM00228. PDZ. 1 hit.
SUPFAMiSSF50156. SSF50156. 1 hit.
SSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Complete.

B0BNB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALKAGRGA NWSLRAWRAL GGIFWRKGPL LAPDLRALLT SGTPDPQARM
60 70 80 90 100
TYGTPSLPAR VPLGVLASRA NLTSGTPDLW VRLTVGTPGS SDQEDCGSPG
110 120 130 140 150
SRRREWLAVA LGAGGAVLLL LWGWGRGPST VLAAVPAPPP TSPRSQYNFI
160 170 180 190 200
ADVVEKTAPA VVYIEILDRH PFSGREVPIS NGSGFIVASD GLIVTNAHVV
210 220 230 240 250
ADRRRVRVRL PSGDTYEAMV TAVDPVADIA TLRIQTKEPL PTLPLGRSAD
260 270 280 290 300
VRQGEFVVAM GSPFALQNTI TSGIVSSAQR PARDLGLPQT NVEYIQTDAA
310 320 330 340 350
IDFGNSGGPL VNLDGEVIGV NTMKVTAGIS FAIPSDRLRE FLHRGEKKNS
360 370 380 390 400
WFGISGSQRR YIGVMMLTLT PSILAELQLR EPSFPDVQHG VLIHKVILGS
410 420 430 440 450
PAHRAGLRPA DVILAIGEKM IQNAEDVYEA VRTQSQLAVR IRRGPETLTL

YVTPEVTE
Length:458
Mass (Da):49,094
Last modified:February 26, 2008 - v1
Checksum:i6DF2003B6D1C0B9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130866 Genomic DNA. No translation available.
BC158760 mRNA. Translation: AAI58761.1.
CH473957 Genomic DNA. Translation: EDL91109.1.
RefSeqiNP_001100069.1. NM_001106599.2.
UniGeneiRn.107325.

Genome annotation databases

EnsembliENSRNOT00000037333; ENSRNOP00000030076; ENSRNOG00000022448.
GeneIDi297376.
KEGGirno:297376.
UCSCiRGD:1308906. rat.

Similar proteinsi

Entry informationi

Entry nameiB0BNB9_RAT
AccessioniPrimary (citable) accession number: B0BNB9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: September 27, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported