ID   SH3Y1_RAT               Reviewed;         340 AA.
AC   B0BNA1;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   24-JAN-2024, entry version 76.
DE   RecName: Full=SH3 domain-containing YSC84-like protein 1;
GN   Name=Sh3yl1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts with SH3D19. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SH3YL1 family. {ECO:0000305}.
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DR   EMBL; BC158742; AAI58743.1; -; mRNA.
DR   RefSeq; NP_001102175.1; NM_001108705.2.
DR   AlphaFoldDB; B0BNA1; -.
DR   SMR; B0BNA1; -.
DR   STRING; 10116.ENSRNOP00000060428; -.
DR   PhosphoSitePlus; B0BNA1; -.
DR   PaxDb; 10116-ENSRNOP00000060428; -.
DR   GeneID; 362724; -.
DR   KEGG; rno:362724; -.
DR   UCSC; RGD:1306440; rat.
DR   AGR; RGD:1306440; -.
DR   CTD; 26751; -.
DR   RGD; 1306440; Sh3yl1.
DR   VEuPathDB; HostDB:ENSRNOG00000005522; -.
DR   eggNOG; KOG1843; Eukaryota.
DR   HOGENOM; CLU_015320_2_1_1; -.
DR   InParanoid; B0BNA1; -.
DR   OrthoDB; 37167at2759; -.
DR   PhylomeDB; B0BNA1; -.
DR   TreeFam; TF331022; -.
DR   PRO; PR:B0BNA1; -.
DR   Proteomes; UP000002494; Chromosome 6.
DR   Bgee; ENSRNOG00000005522; Expressed in duodenum and 20 other cell types or tissues.
DR   GO; GO:0032587; C:ruffle membrane; ISO:RGD.
DR   GO; GO:0019902; F:phosphatase binding; ISO:RGD.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISO:RGD.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; ISO:RGD.
DR   GO; GO:1900027; P:regulation of ruffle assembly; ISO:RGD.
DR   CDD; cd11841; SH3_SH3YL1_like; 1.
DR   CDD; cd11525; SYLF_SH3YL1_like; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR035511; SH3YL1_SH3.
DR   InterPro; IPR033643; SYLF_SH3YL1-like.
DR   InterPro; IPR007461; Ysc84_actin-binding.
DR   PANTHER; PTHR15629:SF2; SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR15629; SH3YL1 PROTEIN; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   Pfam; PF04366; Ysc84; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
DR   Genevisible; B0BNA1; RN.
PE   2: Evidence at transcript level;
KW   Reference proteome; SH3 domain.
FT   CHAIN           1..340
FT                   /note="SH3 domain-containing YSC84-like protein 1"
FT                   /id="PRO_0000341563"
FT   DOMAIN          281..340
FT                   /note="SH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00192"
FT   REGION          224..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..238
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   340 AA;  37039 MW;  E270CE133944F421 CRC64;
     MNNPIPSNLK SEAKKAAKIL REFTEITSRN GPDKIIPAHV IAKAKGLAVL SVIKAGFLVT
     ARGGSGIVLA RLPDGKWSAP SAIGIAGLGG GFEIGIEVSD LVIILNYDRA VEAFAKGGNL
     TLGGNFTVAV GPLGRNLEGN VSLRSSAAVF TYCKSRGLFA GISLEGSCLI ERKETNRKFY
     CQDIRAYDIL FGDVPQPAQA EDLYEILNSF TEKYETEGQR INLKKVAREQ RKAKELPPKP
     SSRPQPSRPP VQLNAGSQSN RNEYKLYPEL SSYHEKTGSL SQPIEVTALY SFEGQQPGDL
     NFQAGDRIIV ISKTDSNFDW WEGKLRGQTG IFPANYVTMN
//