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Protein

SH3 domain-containing YSC84-like protein 1

Gene

Sh3yl1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. phosphatidylinositol binding Source: Ensembl

GO - Biological processi

  1. phosphatidylinositol biosynthetic process Source: Ensembl
  2. regulation of ruffle assembly Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
SH3 domain-containing YSC84-like protein 1
Gene namesi
Name:Sh3yl1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi1306440. Sh3yl1.

Subcellular locationi

GO - Cellular componenti

  1. ruffle membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 340340SH3 domain-containing YSC84-like protein 1PRO_0000341563Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriB0BNA1.

Interactioni

Subunit structurei

Interacts with SH3D19.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060428.

Structurei

3D structure databases

ProteinModelPortaliB0BNA1.
SMRiB0BNA1. Positions 271-340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini281 – 34060SH3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the SH3YL1 family.Curated
Contains 1 SH3 domain.PROSITE-ProRule annotation

Keywords - Domaini

SH3 domain

Phylogenomic databases

eggNOGiCOG2930.
GeneTreeiENSGT00510000048137.
HOGENOMiHOG000215564.
HOVERGENiHBG108487.
InParanoidiB0BNA1.
OMAiITVITKT.
OrthoDBiEOG7MPRFM.
PhylomeDBiB0BNA1.
TreeFamiTF331022.

Family and domain databases

InterProiIPR001452. SH3_domain.
IPR007461. Ysc84_actin-binding.
[Graphical view]
PfamiPF04366. DUF500. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BNA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNPIPSNLK SEAKKAAKIL REFTEITSRN GPDKIIPAHV IAKAKGLAVL
60 70 80 90 100
SVIKAGFLVT ARGGSGIVLA RLPDGKWSAP SAIGIAGLGG GFEIGIEVSD
110 120 130 140 150
LVIILNYDRA VEAFAKGGNL TLGGNFTVAV GPLGRNLEGN VSLRSSAAVF
160 170 180 190 200
TYCKSRGLFA GISLEGSCLI ERKETNRKFY CQDIRAYDIL FGDVPQPAQA
210 220 230 240 250
EDLYEILNSF TEKYETEGQR INLKKVAREQ RKAKELPPKP SSRPQPSRPP
260 270 280 290 300
VQLNAGSQSN RNEYKLYPEL SSYHEKTGSL SQPIEVTALY SFEGQQPGDL
310 320 330 340
NFQAGDRIIV ISKTDSNFDW WEGKLRGQTG IFPANYVTMN
Length:340
Mass (Da):37,039
Last modified:February 26, 2008 - v1
Checksum:iE270CE133944F421
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158742 mRNA. Translation: AAI58743.1.
RefSeqiNP_001102175.1. NM_001108705.2.
UniGeneiRn.1163.

Genome annotation databases

EnsembliENSRNOT00000068208; ENSRNOP00000060428; ENSRNOG00000005522.
GeneIDi362724.
KEGGirno:362724.
UCSCiRGD:1306440. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158742 mRNA. Translation: AAI58743.1.
RefSeqiNP_001102175.1. NM_001108705.2.
UniGeneiRn.1163.

3D structure databases

ProteinModelPortaliB0BNA1.
SMRiB0BNA1. Positions 271-340.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060428.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000068208; ENSRNOP00000060428; ENSRNOG00000005522.
GeneIDi362724.
KEGGirno:362724.
UCSCiRGD:1306440. rat.

Organism-specific databases

CTDi26751.
RGDi1306440. Sh3yl1.

Phylogenomic databases

eggNOGiCOG2930.
GeneTreeiENSGT00510000048137.
HOGENOMiHOG000215564.
HOVERGENiHBG108487.
InParanoidiB0BNA1.
OMAiITVITKT.
OrthoDBiEOG7MPRFM.
PhylomeDBiB0BNA1.
TreeFamiTF331022.

Miscellaneous databases

NextBioi681005.
PROiB0BNA1.

Gene expression databases

GenevestigatoriB0BNA1.

Family and domain databases

InterProiIPR001452. SH3_domain.
IPR007461. Ysc84_actin-binding.
[Graphical view]
PfamiPF04366. DUF500. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.

Entry informationi

Entry nameiSH3Y1_RAT
AccessioniPrimary (citable) accession number: B0BNA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: February 26, 2008
Last modified: April 29, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.