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Protein

Histone H3

Gene

H3f3b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H3UniRule annotation
Gene namesi
Name:H3f3bImported
Synonyms:H3f3aImported
ORF Names:rCG_20294Imported, rCG_33771Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2319910. H3f3a.
621095. H3f3b.

Subcellular locationi

  • Chromosome SAAS annotation
  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000003220.
ExpressionAtlasiB0BMY8. baseline and differential.

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000040434.

Structurei

3D structure databases

ProteinModelPortaliB0BMY8.
SMRiB0BMY8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 132HistoneInterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the histone H3 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1745. Eukaryota.
COG2036. LUCA.
HOVERGENiHBG001172.
KOiK11253.
OMAiCHASMAR.
OrthoDBiEOG091G0XGD.
PhylomeDBiB0BMY8.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR007125. Histone_H2A/H2B/H3.
IPR000164. Histone_H3/CENP-A.
PANTHERiPTHR11426. PTHR11426. 1 hit.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PRINTSiPR00622. HISTONEH3.
SMARTiView protein in SMART
SM00428. H3. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00322. HISTONE_H3_1. 1 hit.
PS00959. HISTONE_H3_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B0BMY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARTKQTARK STGGKAPRKQ LATKAARKSA PSTGGVKKPH RYRPGTVALR
60 70 80 90 100
EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSAAI GALQEASEAY
110 120 130
LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
Length:136
Mass (Da):15,328
Last modified:February 26, 2008 - v1
Checksum:i5158ED279E6F9E1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158615 mRNA. Translation: AAI58616.1.
BC159439 mRNA. Translation: AAI59440.1.
CH473985 Genomic DNA. Translation: EDL94833.1.
CH473948 Genomic DNA. Translation: EDM06637.1.
RefSeqiNP_446437.1. NM_053985.2.
XP_002728089.1. XM_002728043.3.
XP_003752732.1. XM_003752684.4.
UniGeneiRn.106155.
Rn.124815.
Rn.198918.
Rn.29857.

Genome annotation databases

GeneIDi100361558.
117056.
KEGGirno:100361558.
rno:117056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158615 mRNA. Translation: AAI58616.1.
BC159439 mRNA. Translation: AAI59440.1.
CH473985 Genomic DNA. Translation: EDL94833.1.
CH473948 Genomic DNA. Translation: EDM06637.1.
RefSeqiNP_446437.1. NM_053985.2.
XP_002728089.1. XM_002728043.3.
XP_003752732.1. XM_003752684.4.
UniGeneiRn.106155.
Rn.124815.
Rn.198918.
Rn.29857.

3D structure databases

ProteinModelPortaliB0BMY8.
SMRiB0BMY8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000040434.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100361558.
117056.
KEGGirno:100361558.
rno:117056.

Organism-specific databases

CTDi3021.
RGDi2319910. H3f3a.
621095. H3f3b.

Phylogenomic databases

eggNOGiKOG1745. Eukaryota.
COG2036. LUCA.
HOVERGENiHBG001172.
KOiK11253.
OMAiCHASMAR.
OrthoDBiEOG091G0XGD.
PhylomeDBiB0BMY8.

Gene expression databases

BgeeiENSRNOG00000003220.
ExpressionAtlasiB0BMY8. baseline and differential.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR007125. Histone_H2A/H2B/H3.
IPR000164. Histone_H3/CENP-A.
PANTHERiPTHR11426. PTHR11426. 1 hit.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PRINTSiPR00622. HISTONEH3.
SMARTiView protein in SMART
SM00428. H3. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00322. HISTONE_H3_1. 1 hit.
PS00959. HISTONE_H3_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB0BMY8_RAT
AccessioniPrimary (citable) accession number: B0BMY8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: April 12, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.