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Protein
Submitted name:

Natriuretic peptide A

Gene

Nppa

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

VasoactiveUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Natriuretic peptide AImported
Submitted name:
Natriuretic peptide type A, isoform CRA_bImported
Gene namesi
Name:NppaImported
ORF Names:rCG_30993Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3193. Nppa.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500875498525 – 152Sequence analysisAdd BLAST128

Expressioni

Gene expression databases

BgeeiENSRNOG00000008176.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011005.

Family & Domainsi

Sequence similaritiesi

Belongs to the natriuretic peptide family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IW5F. Eukaryota.
ENOG410ZUY6. LUCA.
HOVERGENiHBG004227.
KOiK12334.
OMAiGCNSFRY.
OrthoDBiEOG091G0SV3.

Family and domain databases

InterProiIPR000663. Natr_peptide.
IPR030480. Natr_peptide_CS.
IPR002407. Natriuretic_peptide_atrial.
[Graphical view]
PfamiPF00212. ANP. 1 hit.
[Graphical view]
PRINTSiPR00711. ANATPEPTIDE.
PR00710. NATPEPTIDES.
SMARTiSM00183. NAT_PEP. 1 hit.
[Graphical view]
PROSITEiPS00263. NATRIURETIC_PEPTIDE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BMW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSFSITKGF FLFLAFWLPG HIGANPVYSA VSNTDLMDFK NLLDHLEEKM
60 70 80 90 100
PVEDEVMPPQ ALSEQTDEAG AALSSLSEVP PWTGEVNPSQ RDGGALGRGP
110 120 130 140 150
WDPSDRSALL KSKLRALLAG PRSLRRSSCF GGRIDRIGAQ SGLGCNSFRY

RR
Length:152
Mass (Da):16,556
Last modified:February 26, 2008 - v1
Checksum:iD8AAB2191E29519F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158590 mRNA. Translation: AAI58591.1.
CH473968 Genomic DNA. Translation: EDL81089.1.
RefSeqiNP_036744.1. NM_012612.2.
UniGeneiRn.2004.

Genome annotation databases

GeneIDi24602.
KEGGirno:24602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158590 mRNA. Translation: AAI58591.1.
CH473968 Genomic DNA. Translation: EDL81089.1.
RefSeqiNP_036744.1. NM_012612.2.
UniGeneiRn.2004.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi24602.
KEGGirno:24602.

Organism-specific databases

CTDi4878.
RGDi3193. Nppa.

Phylogenomic databases

eggNOGiENOG410IW5F. Eukaryota.
ENOG410ZUY6. LUCA.
HOVERGENiHBG004227.
KOiK12334.
OMAiGCNSFRY.
OrthoDBiEOG091G0SV3.

Gene expression databases

BgeeiENSRNOG00000008176.

Family and domain databases

InterProiIPR000663. Natr_peptide.
IPR030480. Natr_peptide_CS.
IPR002407. Natriuretic_peptide_atrial.
[Graphical view]
PfamiPF00212. ANP. 1 hit.
[Graphical view]
PRINTSiPR00711. ANATPEPTIDE.
PR00710. NATPEPTIDES.
SMARTiSM00183. NAT_PEP. 1 hit.
[Graphical view]
PROSITEiPS00263. NATRIURETIC_PEPTIDE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB0BMW5_RAT
AccessioniPrimary (citable) accession number: B0BMW5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: November 30, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.