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Protein
Submitted name:

Natriuretic peptide A

Gene

Nppa

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionVasoactiveUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Natriuretic peptide AImported
Submitted name:
Natriuretic peptide type A, isoform CRA_bImported
Gene namesi
Name:NppaImported
ORF Names:rCG_30993Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3193. Nppa.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501095890725 – 152Sequence analysisAdd BLAST128

Expressioni

Gene expression databases

BgeeiENSRNOG00000008176.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the natriuretic peptide family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IW5F. Eukaryota.
ENOG410ZUY6. LUCA.
HOVERGENiHBG004227.
KOiK12334.
OMAiCNSFRYR.
OrthoDBiEOG091G0SV3.

Family and domain databases

InterProiView protein in InterPro
IPR000663. Natr_peptide.
IPR030480. Natr_peptide_CS.
IPR002407. Natriuretic_peptide_atrial.
PfamiView protein in Pfam
PF00212. ANP. 1 hit.
PRINTSiPR00711. ANATPEPTIDE.
PR00710. NATPEPTIDES.
SMARTiView protein in SMART
SM00183. NAT_PEP. 1 hit.
PROSITEiView protein in PROSITE
PS00263. NATRIURETIC_PEPTIDE. 1 hit.

Sequencei

Sequence statusi: Complete.

B0BMW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSFSITKGF FLFLAFWLPG HIGANPVYSA VSNTDLMDFK NLLDHLEEKM
60 70 80 90 100
PVEDEVMPPQ ALSEQTDEAG AALSSLSEVP PWTGEVNPSQ RDGGALGRGP
110 120 130 140 150
WDPSDRSALL KSKLRALLAG PRSLRRSSCF GGRIDRIGAQ SGLGCNSFRY

RR
Length:152
Mass (Da):16,556
Last modified:February 26, 2008 - v1
Checksum:iD8AAB2191E29519F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158590 mRNA. Translation: AAI58591.1.
CH473968 Genomic DNA. Translation: EDL81089.1.
RefSeqiNP_036744.1. NM_012612.2.
UniGeneiRn.2004.

Genome annotation databases

GeneIDi24602.
KEGGirno:24602.

Similar proteinsi

Entry informationi

Entry nameiB0BMW5_RAT
AccessioniPrimary (citable) accession number: B0BMW5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2008
Last sequence update: February 26, 2008
Last modified: September 27, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)