ID   B0BMJ1_XENTR            Unreviewed;       284 AA.
AC   B0BMJ1;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=SET domain and mariner transposase fusion {ECO:0000313|Ensembl:ENSXETP00000103653, ECO:0000313|RefSeq:NP_001107735.1};
DE            EC=2.1.1.43 {ECO:0000313|RefSeq:NP_001107735.1};
DE   SubName: Full=Setmar protein {ECO:0000313|EMBL:AAI58451.1};
GN   Name=setmar {ECO:0000313|EMBL:AAI58451.1,
GN   ECO:0000313|Ensembl:ENSXETP00000103653,
GN   ECO:0000313|RefSeq:NP_001107735.1,
GN   ECO:0000313|Xenbase:XB-GENE-490240};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI58451.1};
RN   [1] {ECO:0000313|RefSeq:NP_001107735.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [2] {ECO:0000313|EMBL:AAI58451.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000313|EMBL:AAI58451.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSXETP00000103653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000103653};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA   Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA   Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA   Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA   Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA   Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA   Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA   Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [4] {ECO:0000313|Ensembl:ENSXETP00000103653}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2021) to UniProtKB.
RN   [5] {ECO:0000313|RefSeq:NP_001107735.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
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DR   EMBL; BC158450; AAI58451.1; -; mRNA.
DR   RefSeq; NP_001107735.1; NM_001114263.1.
DR   STRING; 8364.ENSXETP00000044606; -.
DR   PaxDb; 8364-ENSXETP00000059218; -.
DR   Ensembl; ENSXETT00000112806; ENSXETP00000103653; ENSXETG00000032592.
DR   GeneID; 100135741; -.
DR   KEGG; xtr:100135741; -.
DR   AGR; Xenbase:XB-GENE-490240; -.
DR   CTD; 6419; -.
DR   Xenbase; XB-GENE-490240; setmar.
DR   HOGENOM; CLU_020840_3_3_1; -.
DR   OMA; VDSMVPK; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Bgee; ENSXETG00000032592; Expressed in 4-cell stage embryo and 10 other cell types or tissues.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0140938; F:histone H3 methyltransferase activity; IEA:UniProt.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd10544; SET_SETMAR; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          59..115
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          118..242
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          262..278
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
SQ   SEQUENCE   284 AA;  31042 MW;  2A73FB93924D106F CRC64;
     MAQTGPSAAA MAPEDVCCGT ERLAVPVSGP WENLPAFQYT PELIAGPGAE QDPSEVTIQG
     CDCRGSNCVA ELCSCLPHGT NYVRRTIVSG QRPVRECHIM CSCGESCPNR ETQQGLQYQL
     QLCQRPGKGW GVCTLEDIPS GRFVCEYAGE VLGHEQARSR TLSQNPCANN YIIAVREHLH
     GGQILQTFVD PTHIGNVGRF LNHSCDPNLF MMPVRTHSMV PKLALFAARD IQAGEELCYD
     YSGKFFNQTP ACETLDPEEP SSRKKCQCGA RACSGFLPYE SSLF
//