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Protein

Histone-lysine N-methyltransferase

Gene

setmar

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Name:setmarImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-490240. setmar.

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiB0BMJ1.
ExpressionAtlasiB0BMJ1. baseline.

Structurei

3D structure databases

ProteinModelPortaliB0BMJ1.
SMRiB0BMJ1. Positions 14-282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation

Phylogenomic databases

HOVERGENiHBG093940.
KOiK11433.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BMJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQTGPSAAA MAPEDVCCGT ERLAVPVSGP WENLPAFQYT PELIAGPGAE
60 70 80 90 100
QDPSEVTIQG CDCRGSNCVA ELCSCLPHGT NYVRRTIVSG QRPVRECHIM
110 120 130 140 150
CSCGESCPNR ETQQGLQYQL QLCQRPGKGW GVCTLEDIPS GRFVCEYAGE
160 170 180 190 200
VLGHEQARSR TLSQNPCANN YIIAVREHLH GGQILQTFVD PTHIGNVGRF
210 220 230 240 250
LNHSCDPNLF MMPVRTHSMV PKLALFAARD IQAGEELCYD YSGKFFNQTP
260 270 280
ACETLDPEEP SSRKKCQCGA RACSGFLPYE SSLF
Length:284
Mass (Da):31,042
Last modified:February 25, 2008 - v1
Checksum:i2A73FB93924D106F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158450 mRNA. Translation: AAI58451.1.
RefSeqiNP_001107735.1. NM_001114263.1.
UniGeneiStr.58231.

Genome annotation databases

GeneIDi100135741.
KEGGixtr:100135741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC158450 mRNA. Translation: AAI58451.1.
RefSeqiNP_001107735.1. NM_001114263.1.
UniGeneiStr.58231.

3D structure databases

ProteinModelPortaliB0BMJ1.
SMRiB0BMJ1. Positions 14-282.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100135741.
KEGGixtr:100135741.

Organism-specific databases

CTDi6419.
XenbaseiXB-GENE-490240. setmar.

Phylogenomic databases

HOVERGENiHBG093940.
KOiK11433.

Gene expression databases

BgeeiB0BMJ1.
ExpressionAtlasiB0BMJ1. baseline.

Family and domain databases

InterProiIPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiB0BMJ1_XENTR
AccessioniPrimary (citable) accession number: B0BMJ1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 25, 2008
Last sequence update: February 25, 2008
Last modified: March 3, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.