ID   B0BEZ5_BRAFL            Unreviewed;       276 AA.
AC   B0BEZ5;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Putative alpha-2,8-sialyltransferase {ECO:0000313|EMBL:CAP16259.1};
DE   Flags: Fragment;
GN   Name=siat8 {ECO:0000313|EMBL:CAP16259.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739 {ECO:0000313|EMBL:CAP16259.1};
RN   [1] {ECO:0000313|EMBL:CAP16259.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bfl-16 {ECO:0000313|EMBL:CAP16259.1};
RX   PubMed=18811928;
RA   Harduin-Lepers A., Petit D., Mollicone R., Delannoy P., Petit J.M.,
RA   Oriol R.;
RT   "Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene
RT   family: tandem duplications in early deuterostomes explain most of the
RT   diversity found in the vertebrate ST8Sia genes.";
RL   BMC Evol. Biol. 8:258-258(2008).
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|ARBA:ARBA00004922}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004323}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC       {ECO:0000256|ARBA:ARBA00006003}.
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DR   EMBL; AM901546; CAP16259.1; -; mRNA.
DR   AlphaFoldDB; B0BEZ5; -.
DR   CAZy; GT29; Glycosyltransferase Family 29.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008373; F:sialyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   Gene3D; 3.90.1480.20; Glycosyl transferase family 29; 1.
DR   InterPro; IPR001675; Glyco_trans_29.
DR   InterPro; IPR038578; GT29-like_sf.
DR   InterPro; IPR012163; Sialyl_trans.
DR   PANTHER; PTHR11987; ALPHA-2,8-SIALYLTRANSFERASE; 1.
DR   PANTHER; PTHR11987:SF45; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF00777; Glyco_transf_29; 1.
DR   PIRSF; PIRSF005557; Sialyl_trans; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:CAP16259.1};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAP16259.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DISULFID        64..211
FT                   /evidence="ECO:0000256|PIRSR:PIRSR005557-2"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAP16259.1"
SQ   SEQUENCE   276 AA;  31865 MW;  0353E8338CB7263C CRC64;
     SYSRNAVRKV IDTAKSISIL RSQTHIGDVM HYDIDNHNTF NITKDLYDLL PETSPLEGRL
     FNSCAIVGNS GILLGSGCGQ EIDSHDFVIR CNLAPVTEYV KDVGRKSDLV TMNPSVLPTA
     FGGLKEKHWE EKFVKRLRML EHSMLWIPAF TTINGEKYVQ YTNRIILKND LNIKTLYPTK
     HLAHSIRGQA KTRIKRPSTG LYMYTIATRF CQEIHLYGFF PFTVDVNGRP VRYHYYDNGK
     YNFYDKRRPH SMPVEFQALR RLHDKGALRL LTDKCT
//