SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0BCE1

- RUVC_CHLTB

UniProt

B0BCE1 - RUVC_CHLTB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Crossover junction endodeoxyribonuclease RuvC

Gene
ruvC, CTLon_0759
Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi9 – 91Magnesium By similarity
Metal bindingi70 – 701Magnesium By similarity
Metal bindingi145 – 1451Magnesium By similarity
Metal bindingi148 – 1481Magnesium By similarity

GO - Molecular functioni

  1. crossover junction endodeoxyribonuclease activity Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. nucleic acid binding Source: InterPro

GO - Biological processi

  1. DNA recombination Source: UniProtKB-HAMAP
  2. DNA repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Nuclease

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-797-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Crossover junction endodeoxyribonuclease RuvC (EC:3.1.22.4)
Alternative name(s):
Holliday junction nuclease RuvC
Holliday junction resolvase RuvC
Gene namesi
Name:ruvC
Ordered Locus Names:CTLon_0759
OrganismiChlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Taxonomic identifieri471473 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000794: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 170170Crossover junction endodeoxyribonuclease RuvCUniRule annotationPRO_1000090516Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi471473.CTLon_0759.

Structurei

3D structure databases

ProteinModelPortaliB0BCE1.

Family & Domainsi

Sequence similaritiesi

Belongs to the RuvC family.

Phylogenomic databases

eggNOGiCOG0817.
HOGENOMiHOG000012181.
KOiK01159.
OMAiRQVQEMV.
OrthoDBiEOG6RG044.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
HAMAPiMF_00034. RuvC.
InterProiIPR012337. RNaseH-like_dom.
IPR020563. X-over_junc_endoDNase_Mg_BS.
IPR002176. X-over_junc_endoDNase_RuvC.
[Graphical view]
PfamiPF02075. RuvC. 1 hit.
[Graphical view]
PRINTSiPR00696. RSOLVASERUVC.
SUPFAMiSSF53098. SSF53098. 1 hit.
TIGRFAMsiTIGR00228. ruvC. 1 hit.
PROSITEiPS01321. RUVC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BCE1-1 [UniParc]FASTAAdd to Basket

« Hide

MADLIMGIDP GTLVCGYALI KVENRYHIHP HSFGKVKLSQ KLALAHRYKQ    50
LFTEISTILQ QESPKAVVLE TQYVHKNPQS TIKLGMARGV LLLAASLQDV 100
PVFEYAPNTA KKAAVGKGNA SKKQVQLMVS KLLRVPDLLA EDNEDIADAF 150
ALAMCHAHLA PYQDLKKTLV 170
Length:170
Mass (Da):18,715
Last modified:February 26, 2008 - v1
Checksum:i6078DB9DE3112F94
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM884177 Genomic DNA. Translation: CAP07156.1.
RefSeqiYP_001653847.1. NC_010280.2.

Genome annotation databases

EnsemblBacteriaiCAP07156; CAP07156; CTLon_0759.
GeneIDi5859646.
KEGGictl:CTLon_0759.
PATRICi20383203. VBIChlTra68089_0823.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM884177 Genomic DNA. Translation: CAP07156.1 .
RefSeqi YP_001653847.1. NC_010280.2.

3D structure databases

ProteinModelPortali B0BCE1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471473.CTLon_0759.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP07156 ; CAP07156 ; CTLon_0759 .
GeneIDi 5859646.
KEGGi ctl:CTLon_0759.
PATRICi 20383203. VBIChlTra68089_0823.

Phylogenomic databases

eggNOGi COG0817.
HOGENOMi HOG000012181.
KOi K01159.
OMAi RQVQEMV.
OrthoDBi EOG6RG044.

Enzyme and pathway databases

BioCyci CTRA471473:GHJK-797-MONOMER.

Family and domain databases

Gene3Di 3.30.420.10. 1 hit.
HAMAPi MF_00034. RuvC.
InterProi IPR012337. RNaseH-like_dom.
IPR020563. X-over_junc_endoDNase_Mg_BS.
IPR002176. X-over_junc_endoDNase_RuvC.
[Graphical view ]
Pfami PF02075. RuvC. 1 hit.
[Graphical view ]
PRINTSi PR00696. RSOLVASERUVC.
SUPFAMi SSF53098. SSF53098. 1 hit.
TIGRFAMsi TIGR00228. ruvC. 1 hit.
PROSITEi PS01321. RUVC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCH-1/proctitis.

Entry informationi

Entry nameiRUVC_CHLTB
AccessioniPrimary (citable) accession number: B0BCE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 26, 2008
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi