Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0BB83

- IF2_CHLTB

UniProt

B0BB83 - IF2_CHLTB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi410 – 4178GTPUniRule annotation
Nucleotide bindingi456 – 4605GTPUniRule annotation
Nucleotide bindingi510 – 5134GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-368-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:CTLon_0347
OrganismiChlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Taxonomic identifieri471473 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000794: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 896896Translation initiation factor IF-2PRO_1000093772Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi471473.CTLon_0347.

Structurei

3D structure databases

ProteinModelPortaliB0BB83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini401 – 570170tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni410 – 4178G1By similarity
Regioni435 – 4395G2By similarity
Regioni456 – 4594G3By similarity
Regioni510 – 5134G4By similarity
Regioni546 – 5483G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076906.
KOiK02519.
OMAiMTNKLRI.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BB83-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKAKLTKNL KLKIKNAQLT KAAGLDKLKQ KLAQAGSSDT KNSPASKAQT
60 70 80 90 100
KEKSSKKTAG TPAPAPEVDL GATESTARRI RAKDRSSFAA EPTVTTALPG
110 120 130 140 150
DASHLTLDAI PAIKAPEITS VTQKEQTLRE CTDTSSVQQE EKKESSEETS
160 170 180 190 200
PETPERIEET PIIRTRTEPK SVVSIKPKFG PTGKHINHLL AKTFKAPAKE
210 220 230 240 250
TKAASTEETT QQQPRQNDAA SHNNKQQPSG TSSRPASSAP SYRRESTSNN
260 270 280 290 300
NNNAKRGSER DRSKRSDESV KAFTGRDRYG LNEGSSEEDK WRKKRVHKTK
310 320 330 340 350
KQAEEHVVQC PAHIKIALPI TVKDLAAEMK LKASELIQKL FIHGMTYVVN
360 370 380 390 400
DVLDSQTVVE YIGLEFGCTI EIDSSAKEKL CLVENTVRDE VNATDPEKLI
410 420 430 440 450
IRSPIVAFMG HVDHGKTTII DALRQSNMAA SEAGAITQHT GAFKCTTPVG
460 470 480 490 500
EITVLDTPGH EAFSAMRARG AEVCDIVVLV VAGDEGIKEQ TIEAIEHAKG
510 520 530 540 550
ANITIVVAIN KCDKPNFNVE TVYRQLAELD LLPEAWGGSI ATINTSAKTG
560 570 580 590 600
EGLQDLLEML ALQAEVLELK ADPSARARGL VIESELHKGL GAVATVLVQN
610 620 630 640 650
GTLHLGEALV FNDCYGKVKT MHDEHNQLLQ SATPSTPVLI TGLSAIPKAG
660 670 680 690 700
DPFIVVKNEK VAKEIISARL AGQQRSAALQ KKRPNFDAVL QNKKTLKLII
710 720 730 740 750
KADVQGSIEA LAHSILNIRS EKVDVEILSS GVGDISESDI RLASASKATV
760 770 780 790 800
IGFHTSVESH AEPLIKNLNV KVCLFDIIYH AVDAIKEIMT GLLDPIAEEK
810 820 830 840 850
NLGAAEIKAT FKSSQLGTIY GCLVTEGTVV RNQKIRIIRD KEVLWKGSLS
860 870 880 890
SLKRLKEDVK EVKKGMECGI LLDNYQQAQV GDILQCYEVI YHPQTL
Length:896
Mass (Da):97,378
Last modified:February 26, 2008 - v1
Checksum:i345BA0E5ED81170D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06745.1.
RefSeqiYP_001653447.1. NC_010280.2.

Genome annotation databases

EnsemblBacteriaiCAP06745; CAP06745; CTLon_0347.
GeneIDi5858942.
KEGGictl:CTLon_0347.
PATRICi20382279. VBIChlTra68089_0379.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06745.1 .
RefSeqi YP_001653447.1. NC_010280.2.

3D structure databases

ProteinModelPortali B0BB83.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471473.CTLon_0347.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP06745 ; CAP06745 ; CTLon_0347 .
GeneIDi 5858942.
KEGGi ctl:CTLon_0347.
PATRICi 20382279. VBIChlTra68089_0379.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076906.
KOi K02519.
OMAi MTNKLRI.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci CTRA471473:GHJK-368-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCH-1/proctitis.

Entry informationi

Entry nameiIF2_CHLTB
AccessioniPrimary (citable) accession number: B0BB83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 26, 2008
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3