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B0BB83

- IF2_CHLTB

UniProt

B0BB83 - IF2_CHLTB

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Protein
Translation initiation factor IF-2
Gene
infB, CTLon_0347
Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi410 – 4178GTP By similarity
Nucleotide bindingi456 – 4605GTP By similarity
Nucleotide bindingi510 – 5134GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-KW
  2. GTPase activity Source: UniProtKB-HAMAP
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-368-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:CTLon_0347
OrganismiChlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Taxonomic identifieri471473 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000794: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 896896Translation initiation factor IF-2UniRule annotation
PRO_1000093772Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi471473.CTLon_0347.

Structurei

3D structure databases

ProteinModelPortaliB0BB83.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini401 – 570170tr-type G
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni410 – 4178G1 By similarity
Regioni435 – 4395G2 By similarity
Regioni456 – 4594G3 By similarity
Regioni510 – 5134G4 By similarity
Regioni546 – 5483G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076906.
KOiK02519.
OMAiMTNKLRI.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BB83-1 [UniParc]FASTAAdd to Basket

« Hide

MEKAKLTKNL KLKIKNAQLT KAAGLDKLKQ KLAQAGSSDT KNSPASKAQT    50
KEKSSKKTAG TPAPAPEVDL GATESTARRI RAKDRSSFAA EPTVTTALPG 100
DASHLTLDAI PAIKAPEITS VTQKEQTLRE CTDTSSVQQE EKKESSEETS 150
PETPERIEET PIIRTRTEPK SVVSIKPKFG PTGKHINHLL AKTFKAPAKE 200
TKAASTEETT QQQPRQNDAA SHNNKQQPSG TSSRPASSAP SYRRESTSNN 250
NNNAKRGSER DRSKRSDESV KAFTGRDRYG LNEGSSEEDK WRKKRVHKTK 300
KQAEEHVVQC PAHIKIALPI TVKDLAAEMK LKASELIQKL FIHGMTYVVN 350
DVLDSQTVVE YIGLEFGCTI EIDSSAKEKL CLVENTVRDE VNATDPEKLI 400
IRSPIVAFMG HVDHGKTTII DALRQSNMAA SEAGAITQHT GAFKCTTPVG 450
EITVLDTPGH EAFSAMRARG AEVCDIVVLV VAGDEGIKEQ TIEAIEHAKG 500
ANITIVVAIN KCDKPNFNVE TVYRQLAELD LLPEAWGGSI ATINTSAKTG 550
EGLQDLLEML ALQAEVLELK ADPSARARGL VIESELHKGL GAVATVLVQN 600
GTLHLGEALV FNDCYGKVKT MHDEHNQLLQ SATPSTPVLI TGLSAIPKAG 650
DPFIVVKNEK VAKEIISARL AGQQRSAALQ KKRPNFDAVL QNKKTLKLII 700
KADVQGSIEA LAHSILNIRS EKVDVEILSS GVGDISESDI RLASASKATV 750
IGFHTSVESH AEPLIKNLNV KVCLFDIIYH AVDAIKEIMT GLLDPIAEEK 800
NLGAAEIKAT FKSSQLGTIY GCLVTEGTVV RNQKIRIIRD KEVLWKGSLS 850
SLKRLKEDVK EVKKGMECGI LLDNYQQAQV GDILQCYEVI YHPQTL 896
Length:896
Mass (Da):97,378
Last modified:February 26, 2008 - v1
Checksum:i345BA0E5ED81170D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM884177 Genomic DNA. Translation: CAP06745.1.
RefSeqiYP_001653447.1. NC_010280.2.

Genome annotation databases

EnsemblBacteriaiCAP06745; CAP06745; CTLon_0347.
GeneIDi5858942.
KEGGictl:CTLon_0347.
PATRICi20382279. VBIChlTra68089_0379.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM884177 Genomic DNA. Translation: CAP06745.1 .
RefSeqi YP_001653447.1. NC_010280.2.

3D structure databases

ProteinModelPortali B0BB83.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471473.CTLon_0347.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAP06745 ; CAP06745 ; CTLon_0347 .
GeneIDi 5858942.
KEGGi ctl:CTLon_0347.
PATRICi 20382279. VBIChlTra68089_0379.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076906.
KOi K02519.
OMAi MTNKLRI.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci CTRA471473:GHJK-368-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCH-1/proctitis.

Entry informationi

Entry nameiIF2_CHLTB
AccessioniPrimary (citable) accession number: B0BB83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 26, 2008
Last modified: September 3, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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