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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei45 – 451NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-366-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CTLon_0345
OrganismiChlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Taxonomic identifieri471473 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 241241tRNA pseudouridine synthase BPRO_1000136812Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB0BB81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231223.
KOiK03177.
OMAiDYSFLIP.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

B0BB81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELATESIEG VLLVDKPQGR TSFSLIRSLV RLIGVKKIGH AGTLDPFATG
60 70 80 90 100
VMVMLIGRKF TRLSDIMLFE DKEYAAVAHL GTTTDTYDCD GKIVGRSKKV
110 120 130 140 150
PTMDEVLTCT SYFQGEIQQV PPMFSAKKVQ GKKLYEYARQ GLSIERRFAT
160 170 180 190 200
VTVNLRLVKY EYPRLHFVVQ CSKGTYIRSI AHELGNMLGC GAYLEELRRL
210 220 230 240
RSGSFSIDQC IDGNLLDEPE FNVSPYLRDA NGLILQPAPV L
Length:241
Mass (Da):26,934
Last modified:February 26, 2008 - v1
Checksum:iBB039B792E15BE5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06743.1.
RefSeqiWP_009873551.1. NC_010280.2.

Genome annotation databases

EnsemblBacteriaiCAP06743; CAP06743; CTLon_0345.
KEGGictl:CTLon_0345.
PATRICi20382275. VBIChlTra68089_0377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06743.1.
RefSeqiWP_009873551.1. NC_010280.2.

3D structure databases

ProteinModelPortaliB0BB81.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP06743; CAP06743; CTLon_0345.
KEGGictl:CTLon_0345.
PATRICi20382275. VBIChlTra68089_0377.

Phylogenomic databases

HOGENOMiHOG000231223.
KOiK03177.
OMAiDYSFLIP.

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-366-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_CHLTB
AccessioniPrimary (citable) accession number: B0BB81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 26, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.