Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B

Gene

gatB

Organism
Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation
ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-273-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit BUniRule annotation (EC:6.3.5.-UniRule annotation)
Short name:
Asp/Glu-ADT subunit BUniRule annotation
Gene namesi
Name:gatBUniRule annotation
Ordered Locus Names:CTLon_0254
OrganismiChlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
Taxonomic identifieri471473 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000794 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 488488Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit BPRO_1000095201Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi471473.CTLon_0254.

Structurei

3D structure databases

ProteinModelPortaliB0BAZ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GatB/GatE family. GatB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0064.
HOGENOMiHOG000223742.
KOiK02434.
OMAiESADYRY.
OrthoDBiEOG6RJV5B.

Family and domain databases

Gene3Di1.10.10.410. 1 hit.
HAMAPiMF_00121. GatB.
InterProiIPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR023168. GatB_Yqey_C.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view]
PANTHERiPTHR11659. PTHR11659. 1 hit.
PfamiPF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view]
SMARTiSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMiSSF89095. SSF89095. 1 hit.
TIGRFAMsiTIGR00133. gatB. 1 hit.
PROSITEiPS01234. GATB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0BAZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIAHTEWES VIGLEVHVEL NTESKLFSPA RNHFGDEPNT NISPVCTGMP
60 70 80 90 100
GSLPVLNKDA VRKAVLFGCA VEGDVALFSR FDRKSYFYPD SPRNFQITQY
110 120 130 140 150
EHPIVRGGCI RAVVEGEEKT FELAQTHLED DAGMLKHFGD FAGVDYNRAG
160 170 180 190 200
VPLIEIVSKP CMFSAEDAVA YANALVSILG YIGISDCNME EGSIRFDVNI
210 220 230 240 250
SVRPRGSREL RNKVEIKNMN SFTFMAQALE AEKRRQIEEY LSHPNEDPKK
260 270 280 290 300
VVPAATYRWD PEKKKTVLMR LKERAEDYMY FVEPDLPVLQ ITETYIDEVR
310 320 330 340 350
QTLPELPHSK YMRYITDFDI AEDLAMILVG DRHTAHFFET ATMSCKNYRA
360 370 380 390 400
LSNWITVEFA GRCKAKGKTL PFTGILPEWV AQLVNFIDRG VITGKIAKEI
410 420 430 440 450
ADRMVSSFGE SPEDILRRHP SLLPMTDDHA LRAIVKEVVA QNTASVADYK
460 470 480
NGKAKALGFL VGQIMKRTEG KAPPKRVNEL LLAAMRDM
Length:488
Mass (Da):54,964
Last modified:February 25, 2008 - v1
Checksum:iE1C26BB61D2AA7C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06652.1.
RefSeqiYP_001653355.1. NC_010280.2.

Genome annotation databases

EnsemblBacteriaiCAP06652; CAP06652; CTLon_0254.
KEGGictl:CTLon_0254.
PATRICi20382075. VBIChlTra68089_0279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884177 Genomic DNA. Translation: CAP06652.1.
RefSeqiYP_001653355.1. NC_010280.2.

3D structure databases

ProteinModelPortaliB0BAZ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471473.CTLon_0254.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP06652; CAP06652; CTLon_0254.
KEGGictl:CTLon_0254.
PATRICi20382075. VBIChlTra68089_0279.

Phylogenomic databases

eggNOGiCOG0064.
HOGENOMiHOG000223742.
KOiK02434.
OMAiESADYRY.
OrthoDBiEOG6RJV5B.

Enzyme and pathway databases

BioCyciCTRA471473:GHJK-273-MONOMER.

Family and domain databases

Gene3Di1.10.10.410. 1 hit.
HAMAPiMF_00121. GatB.
InterProiIPR004413. Apn/Gln-ADT_bsu.
IPR017959. Asn/Gln-tRNA_amidoTrfase_suB/E.
IPR006075. Asn/Gln-tRNA_Trfase_suB/E_cat.
IPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR023168. GatB_Yqey_C.
IPR017958. Gln-tRNA_amidoTrfase_suB_CS.
[Graphical view]
PANTHERiPTHR11659. PTHR11659. 1 hit.
PfamiPF02934. GatB_N. 1 hit.
PF02637. GatB_Yqey. 1 hit.
[Graphical view]
SMARTiSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMiSSF89095. SSF89095. 1 hit.
TIGRFAMsiTIGR00133. gatB. 1 hit.
PROSITEiPS01234. GATB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UCH-1/proctitis.

Entry informationi

Entry nameiGATB_CHLTB
AccessioniPrimary (citable) accession number: B0BAZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2009
Last sequence update: February 25, 2008
Last modified: March 31, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.