B0B9E6 (DCD_CHLT2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CTL0294

Organism

Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) [Complete proteome] [HAMAP]

Taxonomic identifier

471472 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096415

Sequences

	Sequence		Length	Mass (Da)
	B0B9E6 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 7211BA4921D20701	FASTA	190	21,384
	10 20 30 40 50 60 MGIKEDNWIR KMAIEEGMIE PFADSQVKLH PETGEKLISY GLSSYGYDLR ISREFKVFTN 70 80 90 100 110 120 VYNSLVDPKC FTEDALISIV DDVCIIPPNS FALARSVEYF RIPRNVLTVC IGKSTYARCG 130 140 150 160 170 180 LIVNVTPFEP EWEGYVTIEI SNTTPLPAKV YANEGIAQVL FFEGDAACDV SYAERQGKYQ 190 KQQGITIPFV

References

[1]

"Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates." Thomson N.R., Holden M.T.G., Carder C., Lennard N., Lockey S.J., Marsh P., Skipp P., O'Connor C.D., Goodhead I., Norbertzcak H., Harris B., Ormond D., Rance R., Quail M.A., Parkhill J., Stephens R.S., Clarke I.N. Genome Res. 18:161-171(2008) [PubMed: 18032721] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 434/Bu / ATCC VR-902B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM884176 Genomic DNA. Translation: CAP03733.1.
RefSeq	YP_001654377.1. NC_010287.1.
3D structure databases
ProteinModelPortal	B0B9E6.
ModBase	Search...
Protein-protein interaction databases
STRING	B0B9E6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5858212.
GenomeReviews	Gene locus CTL0294 in contig AM884176_GR.
KEGG	ctb:CTL0294.
PATRIC	20376086. VBIChlTra32542_0318.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	IFRHIPG.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CTRA471472:CTL0294-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CHLT2

Accession

Primary (citable) accession number: B0B9E6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program