Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei378 – 3781UniRule annotation
Active sitei493 – 4931UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCTRA471472:GJ9M-663-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:CTL0633
OrganismiChlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Taxonomic identifieri471472 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000795: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 525525Glucose-6-phosphate isomerasePRO_1000125705Add
BLAST

Proteomic databases

PRIDEiB0B7U7.

Interactioni

Protein-protein interaction databases

STRINGi471472.CTL0633.

Structurei

3D structure databases

ProteinModelPortaliB0B7U7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0B7U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMGKGFLDCE SLVALQEMAL HPIDLTASGC LSEERIQKNS LSVEGFTYSY
60 70 80 90 100
ATERVDDRCL EALQGLTEER ELIKQMECMQ QGAIMNRIEG FQSESRPVLH
110 120 130 140 150
TATRAWVRDQ DLHEEAAAIA RHSKEEALRL AEFLYIARAK FSTLVQIGIG
160 170 180 190 200
GSELGPKAMY FAMQGSCPSD KRIFFVSNID PDNAAEVLRE IDLEQTLVVV
210 220 230 240 250
VSKSGTTLEP AANEELFRQA YQNKGLSIAE HFVAVTSQGS PMDDKSRYLE
260 270 280 290 300
VFHLWDSIGG RFSATSMVGG VVLGFAFGYE AFIEFLQGAA AIDAHALTPK
310 320 330 340 350
MRENLPLLSA MLGVWNRNLL GYPTTAVIPY STGLKYFTAH LQQCGMESNG
360 370 380 390 400
KSISREGKEI SFRTSPIIWG DVGTNCQHSF FQSLHQGTDI VPVEFIGFLH
410 420 430 440 450
NQRGLDCVLS GSSSSQKLFA NLVAQSLALA QGRDNANPNK RFKGNSPSSI
460 470 480 490 500
LVAQQLSPRI AGSLLAFYEH KFAFQGFCWG INSFDQEGVS LGKELATQII
510 520
GIMSGNAPVE FPEARGVLRL FNVLT
Length:525
Mass (Da):57,700
Last modified:February 26, 2008 - v1
Checksum:iBF49762A614C6ADE
GO

Sequence cautioni

The sequence AAA75628.1 differs from that shown. Reason: Frameshift at positions 469, 500 and 524. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti135 – 14511YIARAKFSTLV → ACLQVDSRGSP in AAA75628 (PubMed:7543468).CuratedAdd
BLAST
Sequence conflicti150 – 1501G → K in AAA75628 (PubMed:7543468).Curated
Sequence conflicti189 – 1891R → L in AAA75628 (PubMed:7543468).Curated
Sequence conflicti247 – 2471R → A in AAA75628 (PubMed:7543468).Curated
Sequence conflicti382 – 3821Missing in AAA75628 (PubMed:7543468).Curated
Sequence conflicti412 – 4121S → T in AAA75628 (PubMed:7543468).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884176 Genomic DNA. Translation: CAP04073.1.
L40822 Genomic DNA. Translation: AAA75628.1. Frameshift.
PIRiF71521.
RefSeqiYP_001654706.1. NC_010287.1.

Genome annotation databases

EnsemblBacteriaiCAP04073; CAP04073; CTL0633.
GeneIDi5858722.
KEGGictb:CTL0633.
PATRICi20376842. VBIChlTra32542_0683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM884176 Genomic DNA. Translation: CAP04073.1.
L40822 Genomic DNA. Translation: AAA75628.1. Frameshift.
PIRiF71521.
RefSeqiYP_001654706.1. NC_010287.1.

3D structure databases

ProteinModelPortaliB0B7U7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471472.CTL0633.

Proteomic databases

PRIDEiB0B7U7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP04073; CAP04073; CTL0633.
GeneIDi5858722.
KEGGictb:CTL0633.
PATRICi20376842. VBIChlTra32542_0683.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciCTRA471472:GJ9M-663-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 434/Bu / ATCC VR-902B.
  2. "Characterization of late gene promoters of Chlamydia trachomatis."
    Fahr M.J., Douglas A.L., Xia W., Hatch T.P.
    J. Bacteriol. 177:4252-4260(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 135-525.

Entry informationi

Entry nameiG6PI_CHLT2
AccessioniPrimary (citable) accession number: B0B7U7
Secondary accession number(s): O84382, Q46402
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 26, 2008
Last modified: January 7, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.