Skip Header

Contribute Send feedback
Read comments (0) or add your own

B0B7L3 (RNC_CHLT2) Reviewed, UniProtKB/Swiss-Prot

Last modified August 10, 2010. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
Customize displayNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:CTL0549
OrganismChlamydia trachomatis (strain L2/434/Bu / ATCC VR-902B) [Complete proteome] [HAMAP]
Taxonomic identifier471472 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104

Subcellular location

Cytoplasm By similarity HAMAP MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processRNA processing

Inferred from electronic annotation. Source: InterPro

rRNA catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondouble-stranded RNA binding

Inferred from electronic annotation. Source: InterPro

ribonuclease III activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 231231Ribonuclease 3 HAMAP MF_00104
PRO_1000094099

Regions

Domain7 – 135129RNase III
Domain160 – 22970DRBM

Sequences

Sequence LengthMass (Da)Tools
B0B7L3-1 [UniParc].

Last modified February 26, 2008. Version 1.
Checksum: 9AC603E1DB831C6A

FASTA23125,595
        10         20         30         40         50         60 
MQHTVDIQAI ESKLNFTFSH PRLLITALTH PSYRNEFPSA EEDSERLEFL GDAVLGLVVT 

        70         80         90        100        110        120 
EHLFLLFPAL NEGLLSTTRA ALVNAEACFE YTQKLSLGEH LLIGRGEKMQ SHRGKISAYA 

       130        140        150        160        170        180 
NLFEAILGAV YLDGGLSPAR QIIVPLLPDK ESILPLMLVN PKNRLQQFTQ QTLKVLPSYK 

       190        200        210        220        230 
ALPWKSEDGS PGYHVQVFVN GDLWGEGFAG SKKEAEKLAA KQALSTHDNK N 

« Hide

References

[1]"Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates."
Thomson N.R., Holden M.T.G., Carder C., Lennard N., Lockey S.J., Marsh P., Skipp P., O'Connor C.D., Goodhead I., Norbertzcak H., Harris B., Ormond D., Rance R., Quail M.A., Parkhill J., Stephens R.S., Clarke I.N.
Genome Res. 18:161-171(2008) [PubMed: 18032721] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM884176 Genomic DNA. Translation: CAP03989.1.
RefSeqYP_001654626.1.

3D structure databases

ProteinModelPortalB0B7L3.
SMRB0B7L3. Positions 6-226.
ModBaseSearch...

Genome annotation databases

GeneID5858279.
GenomeReviewsGene locus CTL0549 in contig AM884176_GR.
KEGGctb:CTL0549.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG744556.
OMATHASART.
ProtClustDBPRK00102.

Enzyme and pathway databases

BioCycCTRA471472:CTL0549-MONOMER.

Family and domain databases

HAMAPMF_00104. RNase_III.
[Tree]
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like.
IPR000999. RNase_III.
IPR011907. RNase_III_bac.
[Graphical view]
Gene3DG3DSA:3.30.160.20. dsRNA-bd-like. 1 hit.
G3DSA:1.10.1520.10. RNase_III. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_CHLT2
AccessionPrimary (citable) accession number: B0B7L3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 26, 2008
Last modified: August 10, 2010
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families