B0AMY5 (B0AMY5_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA1 EMBL EDR20526.1
Synonyms:	msrA HAMAP MF_01401
ORF Names:	BAC_1861 EMBL EDR20526.1

Organism

Bacillus anthracis str. A0488 EMBL EDR20526.1

Taxonomic identifier

486624 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL EDR20526.1
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	B0AMY5 [UniParc]. Last modified February 26, 2008. Version 1. Checksum: 8468283B293CE745	FASTA	178	20,618
	10 20 30 40 50 60 MSEKTYELAT FAGGCFWCMV KPFDELPDIH KVLSGYAGGH VENPTYEQVK AGTSGHLEVV 70 80 90 100 110 120 QITFDPSIFP YEKLLNLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHTETQK ELAEKSKHSL 130 140 150 160 170 AESGMFKDPI VTEIRPAAPF YEAEEYHQHF YKKNPEKYAT EQKESGREDF IKENWQKK

References

[1]	"Genome sequence of Bacillus anthracis A0488." Dodson R.J., Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D., Sutton G., Brettin T.S. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A0488 EMBL EDR20526.1.
[2]	Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D., Brettin T.S. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A0488 EMBL EDR20526.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABJC01000002 Genomic DNA. Translation: EDR20526.1.
3D structure databases
ProteinModelPortal	B0AMY5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	24640865. VBIBacAnt7575_1435.
Phylogenomic databases
OMA	LVELYWT.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0AMY5_BACAN

Accession

Primary (citable) accession number: B0AMY5

Entry history

Integrated into UniProtKB/TrEMBL:	February 26, 2008
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)