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Protein
Submitted name:

RASSF1A tumor suppressor

Gene

Rassf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingSAAS annotation, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
RASSF1A tumor suppressorImported
Submitted name:
Ras association (RalGDS/AF-6) domain family 1, isoform CRA_bImported
Gene namesi
Name:Rassf1Imported
ORF Names:mCG_18873Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1928386 Rassf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000010067

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 101Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini194 – 288Ras-associatingInterPro annotationAdd BLAST95
Domaini290 – 337SARAHInterPro annotationAdd BLAST48

Phylogenomic databases

eggNOGiENOG410IPAE Eukaryota
ENOG4111HS2 LUCA
HOVERGENiHBG054362
KOiK09850

Family and domain databases

CDDicd00029 C1, 1 hit
InterProiView protein in InterPro
IPR033614 C-RASSF
IPR002219 PE/DAG-bd
IPR000159 RA_dom
IPR033600 RASSF1
IPR011524 SARAH_dom
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR22738 PTHR22738, 1 hit
PTHR22738:SF12 PTHR22738:SF12, 1 hit
PfamiView protein in Pfam
PF00130 C1_1, 1 hit
PF16517 Nore1-SARAH, 1 hit
PF00788 RA, 1 hit
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00314 RA, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit
PS50951 SARAH, 1 hit
PS00479 ZF_DAG_PE_1, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A9YZW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEPELIEL RELAPSGRIG PGRTRLERAN ALRIAPGTTR NPSQQHVPGR
60 70 80 90 100
GHRFQPAGPT THTWCDLCGD FIWGVVRKGL QCAHCKFTCH YRCRALVCLD
110 120 130 140 150
CCGPRDLGWD SALERDTNVD EAVERETPDL SQAETEQKIK DYNGQINSNL
160 170 180 190 200
FMSLNKDGSY TGFIKVQLKL VRPVSVPSSK KPPSLQDARR GTGRSTAVKR
210 220 230 240 250
RTSFYLPKDA IKHLHVLSRT RAREVIEALL RKFMVVDDPR KFALFERTER
260 270 280 290 300
HGQVYLRKLS DDEQPLKLRL LAGPSEKALS FVLKENDSGE VNWDAFSMPE
310 320 330 340
LHNFLRILQR EEEEHLRQIL QKYSRCRQKI QEALHACPLG
Length:340
Mass (Da):38,789
Last modified:February 5, 2008 - v1
Checksum:i7DEBA4AEE705757F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU314810 mRNA Translation: ABY27299.1
CH466560 Genomic DNA Translation: EDL21198.1
RefSeqiNP_001230677.1, NM_001243748.1
UniGeneiMm.12091
Mm.488708

Genome annotation databases

GeneIDi56289
KEGGimmu:56289

Similar proteinsi

Entry informationi

Entry nameiA9YZW8_MOUSE
AccessioniPrimary (citable) accession number: A9YZW8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health