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A9YWS9

- A9YWS9_CAVPO

UniProt

A9YWS9 - A9YWS9_CAVPO

Protein
Submitted name:

Alpha-enolase

Gene

Eno1

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (05 Feb 2008)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei158 – 1581SubstrateUniRule annotation
    Binding sitei167 – 1671SubstrateUniRule annotation
    Active sitei210 – 2101Proton donorUniRule annotation
    Binding sitei293 – 2931SubstrateUniRule annotation
    Binding sitei318 – 3181SubstrateUniRule annotation
    Active sitei343 – 3431Proton acceptorUniRule annotation
    Binding sitei394 – 3941SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. phosphopyruvate hydratase activity Source: InterPro

    GO - Biological processi

    1. glycolytic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Alpha-enolaseImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:Eno1Imported
    OrganismiCavia porcellus (Guinea pig)
    Taxonomic identifieri10141 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiCaviidaeCavia
    ProteomesiUP000005447: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. phosphopyruvate hydratase complex Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi10141.ENSCPOP00000005241.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni370 – 3734Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG0148.
    GeneTreeiENSGT00550000074560.
    HOGENOMiHOG000072174.
    HOVERGENiHBG000067.
    InParanoidiA9YWS9.
    OMAiVSEKSCN.
    OrthoDBiEOG776SQ1.
    TreeFamiTF300391.

    Family and domain databases

    Gene3Di3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    HAMAPiMF_00318. Enolase.
    InterProiIPR000941. Enolase.
    IPR020810. Enolase_C.
    IPR029065. Enolase_C-like.
    IPR020809. Enolase_CS.
    IPR020811. Enolase_N.
    IPR029017. Enolase_N_like.
    [Graphical view]
    PANTHERiPTHR11902. PTHR11902. 1 hit.
    PfamiPF00113. Enolase_C. 1 hit.
    PF03952. Enolase_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001400. Enolase. 1 hit.
    PRINTSiPR00148. ENOLASE.
    SUPFAMiSSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    TIGRFAMsiTIGR01060. eno. 1 hit.
    PROSITEiPS00164. ENOLASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A9YWS9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSILKVHARE IFDSRGNPTV EVDLYTAKGL FRAAVPSGAS TGIYEALELR    50
    DNDKTRYMGK GVSKAVEHIN NTIAPALVSK KLNVVEQEKI DKLMIEMDGT 100
    ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN AEVILPVPAF 150
    NVINGGSHAG NKLAMQEFMI LPVGADSFKE AMRIGAEVYH NLKNVIKEKY 200
    GKDATNVGDE GGFAPNILEN KEALELLKNA IGKAGYTDKV VIGMDVAASE 250
    FFRSGKYDLD FKSPDDSSRY ISPDQLGDLY KSFIKDYPVV SIEDPFDQDD 300
    WDAWQKFTAS VGIQVVGDDL TVTNPKRIAK AVNEKACNCL LLKVNQIGSV 350
    TESLQACKLA HSNGWGVMVS HRSGETEDTF IADLVVGLST GQIKTGAPCR 400
    SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK 434
    Length:434
    Mass (Da):47,194
    Last modified:February 5, 2008 - v1
    Checksum:iC4B7B9E0095ADB1B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAKN02028899 Genomic DNA. No translation available.
    EU306867 mRNA. Translation: ABY21425.1.
    RefSeqiNP_001166544.1. NM_001173073.1.
    XP_005004262.1. XM_005004205.1.
    XP_005004263.1. XM_005004206.1.

    Genome annotation databases

    EnsembliENSCPOT00000005874; ENSCPOP00000005241; ENSCPOG00000005812.
    GeneIDi100306968.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAKN02028899 Genomic DNA. No translation available.
    EU306867 mRNA. Translation: ABY21425.1 .
    RefSeqi NP_001166544.1. NM_001173073.1.
    XP_005004262.1. XM_005004205.1.
    XP_005004263.1. XM_005004206.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10141.ENSCPOP00000005241.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSCPOT00000005874 ; ENSCPOP00000005241 ; ENSCPOG00000005812 .
    GeneIDi 100306968.

    Organism-specific databases

    CTDi 2023.

    Phylogenomic databases

    eggNOGi COG0148.
    GeneTreei ENSGT00550000074560.
    HOGENOMi HOG000072174.
    HOVERGENi HBG000067.
    InParanoidi A9YWS9.
    OMAi VSEKSCN.
    OrthoDBi EOG776SQ1.
    TreeFami TF300391.

    Family and domain databases

    Gene3Di 3.20.20.120. 1 hit.
    3.30.390.10. 1 hit.
    HAMAPi MF_00318. Enolase.
    InterProi IPR000941. Enolase.
    IPR020810. Enolase_C.
    IPR029065. Enolase_C-like.
    IPR020809. Enolase_CS.
    IPR020811. Enolase_N.
    IPR029017. Enolase_N_like.
    [Graphical view ]
    PANTHERi PTHR11902. PTHR11902. 1 hit.
    Pfami PF00113. Enolase_C. 1 hit.
    PF03952. Enolase_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001400. Enolase. 1 hit.
    PRINTSi PR00148. ENOLASE.
    SUPFAMi SSF51604. SSF51604. 1 hit.
    SSF54826. SSF54826. 1 hit.
    TIGRFAMsi TIGR01060. eno. 1 hit.
    PROSITEi PS00164. ENOLASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank."
      Simpanya M.F., Wistow G., Gao J., David L.L., Giblin F.J., Mitton K.P.
      Mol. Vis. 14:2413-2427(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LensImported.
    2. "A high-resolution map of human evolutionary constraint using 29 mammals."
      Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
      , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
      Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2NImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: 2NImported.

    Entry informationi

    Entry nameiA9YWS9_CAVPO
    AccessioniPrimary (citable) accession number: A9YWS9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 5, 2008
    Last sequence update: February 5, 2008
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3