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Protein

Uronate isomerase

Gene

uxaC

Organism
Brucella suis (strain ATCC 23445 / NCTC 10510)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciBSUI470137:GJIC-2807-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:BSUIS_B0804
OrganismiBrucella suis (strain ATCC 23445 / NCTC 10510)
Taxonomic identifieri470137 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000008545 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uronate isomerasePRO_1000082959Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA9WZA1.
SMRiA9WZA1. Positions 1-466.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A9WZA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNPDRLFS AEPGTREIAR RLFASVEKLP IISPHGHTEP IWYARNEAFP
60 70 80 90 100
DPASLFVKPD HYITRMLYSQ GHSLESLGIA SRDGRPSETD ARKIWRLFAT
110 120 130 140 150
NWYLFRATPS RLWFEHAMET VFGITERLSQ ENADRIFDAI ADQLTQPHMR
160 170 180 190 200
PRALYDRFNI EAISTTDAAT DPLIYHDEVI ASGWHGRIIP AYRPDAAVDA
210 220 230 240 250
GRPDFASEVE KLVGVAGTPL TWQGYLDAHR NRREYFKRRG ATSSDHGHPT
260 270 280 290 300
AQTADLSAGD ASRLFDRVIK GNASTSDAEM FRAQMLTEMA RMSIDDGLVM
310 320 330 340 350
QIHPGSFRNH NPTVFERFGL DKGADIPRQT GFVDQLKPLL DGFGNDPRLT
360 370 380 390 400
VILFTLDETA YSRELAPLAG DYPALKLGPA WWFFDSPEGI LRYRKLTTET
410 420 430 440 450
AGFYNTVGFN DDTRAYLSIP ARHDMARRVD CAYLAGLVAD HRLEEDEAYE
460
VAHDLAYRLA KQTYKL
Length:466
Mass (Da):52,714
Last modified:February 5, 2008 - v1
Checksum:iCC7F32CFE9CD3E0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000912 Genomic DNA. Translation: ABY39767.1.
RefSeqiWP_006073937.1. NC_010167.1.

Genome annotation databases

EnsemblBacteriaiABY39767; ABY39767; BSUIS_B0804.
KEGGibmt:BSUIS_B0804.
PATRICi17866057. VBIBruSui83806_0847.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000912 Genomic DNA. Translation: ABY39767.1.
RefSeqiWP_006073937.1. NC_010167.1.

3D structure databases

ProteinModelPortaliA9WZA1.
SMRiA9WZA1. Positions 1-466.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY39767; ABY39767; BSUIS_B0804.
KEGGibmt:BSUIS_B0804.
PATRICi17866057. VBIBruSui83806_0847.

Phylogenomic databases

HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciBSUI470137:GJIC-2807-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_BRUSI
AccessioniPrimary (citable) accession number: A9WZA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.