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A9WY35

- GLSA_BRUSI

UniProt

A9WY35 - GLSA_BRUSI

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Protein
Glutaminase
Gene
glsA, BSUIS_B0346
Organism
Brucella suis (strain ATCC 23445 / NCTC 10510)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei67 – 671Substrate By similarity
Binding sitei118 – 1181Substrate By similarity
Binding sitei162 – 1621Substrate By similarity
Binding sitei169 – 1691Substrate By similarity
Binding sitei193 – 1931Substrate By similarity
Binding sitei245 – 2451Substrate By similarity
Binding sitei263 – 2631Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBSUI470137:GJIC-2357-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:BSUIS_B0346
OrganismiBrucella suis (strain ATCC 23445 / NCTC 10510)
Taxonomic identifieri470137 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000008545: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317GlutaminaseUniRule annotation
PRO_1000079072Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi470137.BSUIS_B0346.

Structurei

3D structure databases

ProteinModelPortaliA9WY35.
SMRiA9WY35. Positions 5-309.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQCSVGVT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A9WY35-1 [UniParc]FASTAAdd to Basket

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MSSSSDAIKA ALEKGRAAGL SATGGKNADY IPFLASVPSD LFGLAVVTAD    50
GQTFKTGDAD FAFAIESISK VFTLALVMEE IGPDSVREKV GADPTGLPFN 100
SVIALELHNG KSLSPLVNAG AIATASLVPG DTADARWNNI LECQCGFAGR 150
RLKLSNEVNQ SEQTTNFHNR AIAWLLYSAG TCYSDPMEAV DIYTRQCSTL 200
VTATDLATMG ATLAAGGVNP ISGKRMVSAG NVAPILAEMT MEGLYTASGD 250
WAYTVGLPGK SGVGGGIMAV VPGELAIAAF SPPLDPAGNS VKAMAAVAAV 300
ADSLGHNLYT TRGKVSS 317
Length:317
Mass (Da):32,443
Last modified:February 5, 2008 - v1
Checksum:iA7B2A39A9A7EB02D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000912 Genomic DNA. Translation: ABY39351.1.
RefSeqiYP_001622173.1. NC_010167.1.

Genome annotation databases

EnsemblBacteriaiABY39351; ABY39351; BSUIS_B0346.
GeneIDi5836428.
KEGGibmt:BSUIS_B0346.
PATRICi17865079. VBIBruSui83806_0358.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000912 Genomic DNA. Translation: ABY39351.1 .
RefSeqi YP_001622173.1. NC_010167.1.

3D structure databases

ProteinModelPortali A9WY35.
SMRi A9WY35. Positions 5-309.
ModBasei Search...

Protein-protein interaction databases

STRINGi 470137.BSUIS_B0346.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABY39351 ; ABY39351 ; BSUIS_B0346 .
GeneIDi 5836428.
KEGGi bmt:BSUIS_B0346.
PATRICi 17865079. VBIBruSui83806_0358.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QCSVGVT.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci BSUI470137:GJIC-2357-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23445 / NCTC 10510.

Entry informationi

Entry nameiGLSA_BRUSI
AccessioniPrimary (citable) accession number: A9WY35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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