A9WV14 (A9WV14_RENSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	RSal33209_3323

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY25035.1

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL ABY25035.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	5	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A9WV14 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 12A138E6AAB4A078	FASTA	169	19,179
	10 20 30 40 50 60 MGGGCFWCLD AIYQKTKGVS EVVSGYTGGH TRHPDYESVS AGITGHAEVV AVTFDETVIP 70 80 90 100 110 120 EEVILDLFFV SHDPTTLNRQ GYDVGTQYRS SMFYVDAEQE EAFNAAIMRA QPLWSDPIVT 130 140 150 160 EITRLPDFYR AEEYHQDFYA KHPEQGYCQV IINPKLAKAR KYYSSWLTT

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY25035.1.
RefSeq	YP_001626449.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WV14.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WV14.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5822861.
GenomeReviews	Gene locus RSal33209_3323 in contig CP000910_GR.
KEGG	rsa:RSal33209_3323.
PATRIC	23080123. VBIRenSal21953_3457.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG748152.
OMA	PYCRFVI.
ProtClustDB	CLSK959948.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_3323-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9WV14_RENSM

Accession

Primary (citable) accession number: A9WV14

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)