Skip Header

Contribute Send feedback
Read comments (?) or add your own

A9WUV0 (A9WUV0_RENSM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase HAMAP-Rule MF_00451
Short name=NDK HAMAP-Rule MF_00451
Short name=NDP kinase HAMAP-Rule MF_00451
EC=2.7.4.6 HAMAP-Rule MF_00451
Alternative name(s):
Nucleoside-2-P kinase HAMAP-Rule MF_00451
Gene names
Name:ndk HAMAP-Rule MF_00451
Ordered Locus Names:RSal33209_3255
OrganismRenibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY24971.1
Taxonomic identifier288705 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium ›

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. RuleBase RU004013 HAMAP-Rule MF_00451

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00451

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00451

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00451.

Sequence similarities

Belongs to the NDK family. HAMAP-Rule MF_00451 RuleBase RU004011

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1211Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451
Binding site111ATP By similarity HAMAP-Rule MF_00451
Binding site591ATP By similarity HAMAP-Rule MF_00451
Binding site871ATP By similarity HAMAP-Rule MF_00451
Binding site931ATP By similarity HAMAP-Rule MF_00451
Binding site1041ATP By similarity HAMAP-Rule MF_00451

Sequences

Sequence LengthMass (Da)Tools
A9WUV0 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 266AD3BE68AA6105

FASTA13714,935
        10         20         30         40         50         60 
MSLERTLVLV KPDGVARNLS GAILARIEAK GYRLAELKRT QATRAQLEEH YAEHAGKPFY 

        70         80         90        100        110        120 
EPLVGFMLSG PVVAAIFKGE RVIEGFRSLA GATDPTVAAP GTIRGDFGRD WGLKVQQNLV 

       130 
HGSDSVESAE REIGIWF

« Hide

References

[1]"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor."
Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S.
J. Bacteriol. 190:6970-6982(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000910 Genomic DNA. Translation: ABY24971.1.
RefSeqYP_001626385.1. NC_010168.1.

3D structure databases

ProteinModelPortalA9WUV0.
SMRA9WUV0. Positions 2-137.
ModBaseSearch...

Protein-protein interaction databases

STRING288705.RSal33209_3255.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY24971; ABY24971; RSal33209_3255.
GeneID5823155.
KEGGrsa:RSal33209_3255.
PATRIC23079977. VBIRenSal21953_3388.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0105.
HOGENOMHOG000224564.
KOK00940.
OMAFRVVAMK.

Enzyme and pathway databases

BioCycRSAL288705:GHX1-3255-MONOMER.

Family and domain databases

Gene3D3.30.70.141. 1 hit.
HAMAPMF_00451. NDP_kinase.
InterProIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PANTHERPTHR11349. PTHR11349. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
PROSITEPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9WUV0_RENSM
AccessionPrimary (citable) accession number: A9WUV0
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info