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A9WUU1 (A9WUU1_RENSM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:RSal33209_3246
OrganismRenibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY24962.1
Taxonomic identifier288705 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. SAAS SAAS011529 HAMAP MF_00456

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain285 – 36379PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A9WUU1 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 2436D4070D8A872F

FASTA37739,112
        10         20         30         40         50         60 
MRSDSVVVGG RELLKTASRI VVKVGSSSLT SVSGGISEQA LSQLVDVLAA RKKQGAEIIL 

        70         80         90        100        110        120 
VSSGAIAAGL APLGLARRPK DLATQQSAAS VGQSLLMARY GAAFGSHNVT VSQVLLTAED 

       130        140        150        160        170        180 
LTRRTQYANV YRALERLLNL GVLPIVNEND TVATHEIRFG DNDRLAALVA HLVKADAMVL 

       190        200        210        220        230        240 
LSDVDAVYDG PPNTGARRIE QISSPEDLAG IKIGSVGSAG VGTGGMATKV QAASIAAGFG 

       250        260        270        280        290        300 
TPALVTSAAN AEAALAGADV GTWFSLHGER RPIRLLWLAH LASTHGKLTL DDGAVAAIRE 

       310        320        330        340        350        360 
RHKSLLPAGI KAVSGEFEAG DAVELVDLAG RTFAHGLVNY DAAELPTMLG KKTKDLAGEL 

       370 
GRDYVRAVVH VDDLVLI

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References

[1]"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor."
Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S.
J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000910 Genomic DNA. Translation: ABY24962.1.
RefSeqYP_001626376.1. NC_010168.1.

3D structure databases

ProteinModelPortalA9WUU1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA9WUU1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5823146.
GenomeReviewsGene locus RSal33209_3246 in contig CP000910_GR.
KEGGrsa:RSal33209_3246.
PATRIC23079957. VBIRenSal21953_3378.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Enzyme and pathway databases

BioCycRSAL288705:RSAL33209_3246-MONOMER.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA9WUU1_RENSM
AccessionPrimary (citable) accession number: A9WUU1
Entry history
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info