A9WU17 (A9WU17_RENSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114
Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114

Gene names

Name:	deoC HAMAP MF_00114
Ordered Locus Names:	RSal33209_2966

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY24688.1

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114 SAAS SAAS022979
Ligand	Schiff base SAAS SAAS022979 HAMAP MF_00114
Molecular function	Lyase HAMAP MF_00114 SAAS SAAS022979 EMBL ABY24688.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	155	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	184	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A9WU17 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: A3441FEE84241AA1	FASTA	224	22,692
	10 20 30 40 50 60 MTENIASFID HTLLKPEASE ADVLKVCGEA VNYEFKSVCV NPIWVKTVHQ ALRNSPVLTC 70 80 90 100 110 120 SVVGFPLGAT PTDVQVFEAR GATLDGADEV DMVINIAEAR ASNRGALVDD ISAVADAVHA 130 140 150 160 170 180 GGAILKVIIE TSLLDDAQKV IACEAAVEAG ADFVKTSTGF NGGGATTADV ALMRATVGPS 190 200 210 220 VGVKASGGVR SREDAEAMIA AGASRIGASS GIAIVTGGTG TNAY

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY24688.1.
RefSeq	YP_001626102.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WU17.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WU17.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5824086.
GenomeReviews	Gene locus RSal33209_2966 in contig CP000910_GR.
KEGG	rsa:RSal33209_2966.
PATRIC	23079373. VBIRenSal21953_3092.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG636421.
OMA	IDHTNLK.
ProtClustDB	PRK00507.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_2966-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9WU17_RENSM

Accession

Primary (citable) accession number: A9WU17

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)