A9WS78 (A9WS78_RENSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III alpha subunit EMBL ABY24207.1
EC=2.7.7.7 EMBL ABY24207.1

Gene names

Ordered Locus Names:

RSal33209_2481

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY24207.1

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	1176 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A9WS78 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 49C423A7A4B3FDEA	FASTA	1,176	129,573
	10 20 30 40 50 60 MTGTESSFVH LHNHTEYSML DGAARLTDLF EHTAELGMNS LATTDHGFVF GAFDFWSKAK 70 80 90 100 110 120 NAGIKPIIGV EAYLTPGTAH NDRTRVKWGD GSGKDVAGAG AYTHMTLWSE TTQGMHNLFR 130 140 150 160 170 180 MSSLASLEGY LYKPRMDRDL LQTYGKGLIA STGCPSGEVP TKLGLGLYKE AVQAASDFQD 190 200 210 220 230 240 IFGKGNFYCE LMDHGLDIER NVKADLLKLA KELNLPLVAT NDLHYTHAED ASAHAALLCV 250 260 270 280 290 300 QSGSTLADPK RFKFDADEFY LKSPLEMREL FRDFPDACDN TLLIAERCEV AFDTGASYMP 310 320 330 340 350 360 RFPVPEGENE QSWFVKEVEK GLHYRYPGGI PADVRKQAEF EVGVITQMGF PGYFLVVADF 370 380 390 400 410 420 INWAKNNGIR VGPGRGSGAG SMVAYAMRIT DLDPLKHGLI FERFLNPERV SMPDFDVDFD 430 440 450 460 470 480 DRRRGEVIRY VTEKYGDERV AMIVTYGTIK AKQALKDSSR VLGYPYSTGE RLTKAMPPDV 490 500 510 520 530 540 MGKGMALTDV HNKEAKRYSE AEELRELIKT DPDSQKVFDT AIGIEGLKRQ WGVHAAGVIM 550 560 570 580 590 600 SSDPLIDIIP IMRREQDGQI ITQFDYPTCE GLGLIKMDFL GLRNLTIISD AIENIKLNRD 610 620 630 640 650 660 FDLDLEGLEL DDVPSYELLA RGDTLGVFQL DGGPMRSLLK LMKPDNFEDI SAVLALYRPG 670 680 690 700 710 720 PMGVNSHTNY ALRKNKLQEI TPIHPELEAP LEDILGTTYG LIVYQEQVMA AAQKLAGFSL 730 740 750 760 770 780 GQADILRRAM GKKKKSELDK QQADFFAGMK TNGYSQAAMD ALWKVLESFA DYAFNKAHTA 790 800 810 820 830 840 AYGLISYWTA YLKEHYAAEY MAALLTSVGD DKDKLAIYLN ECRRMGITVL PPDVNESSVN 850 860 870 880 890 900 FTPVDTDIRF GMGAIRNVGA NVVQAMVGAR EEKGAFENFS DYLLKVPAVV CNKRTIESLI 910 920 930 940 950 960 KAGAFDSLGH PRRALVAVHE EAIDSVVVLK RNEAVGQFDL FAGFSDEEAE PGFSTDVPDL 970 980 990 1000 1010 1020 PEWEKKDKLA FERDMLGLYV SDHPLRGLEG VLSQHAEHTI SYLIGEDGLS DGAIVTIAGM 1030 1040 1050 1060 1070 1080 ITSLSRRIAK ASGNAYARAE IEDLGASMEV MFFGQVYGPI STILAEDLIV TIKGRLQKRD 1090 1100 1110 1120 1130 1140 DGSITLNAME LTVPDITEGD GGPVVILLQE HKATESVITS LGDVLGTHPG NSEVRLHLAG 1150 1160 1170 SSSVKVMKLP LHRRVNPNPA LFGDLKVLLG PTCLEA

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY24207.1.
RefSeq	YP_001625621.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WS78.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WS78.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5824235.
GenomeReviews	Gene locus RSal33209_2481 in contig CP000910_GR.
KEGG	rsa:RSal33209_2481.
PATRIC	23078331. VBIRenSal21953_2575.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_2481-MONOMER.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9WS78_RENSM

Accession

Primary (citable) accession number: A9WS78

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)