A9WR29 (A9WR29_RENSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	RSal33209_0001

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY21761.1

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	467 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 DNA-binding HAMAP MF_00377 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	166 – 173	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	A9WR29 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: F9E8A439E2AE0BB1	FASTA	467	52,525
	10 20 30 40 50 60 MNTESNGDIA GSWRKVVKIL EQDEHVSPRQ RGFITLAQAQ GLIGSTLLLA VPNELTREVL 70 80 90 100 110 120 QNQIKGSLDL ALREVFGEDV LCAISIDTDL TPVPEEVRQE VEPDEPSEES RPQPGPPSTS 130 140 150 160 170 180 NEFGRLNPKY LFDTFVIGQS NRFAHAAAVA VAEAPAKAYN PLFIYGDSGL GKTHLLHAIG 190 200 210 220 230 240 HYARRLYNGI RVRYVNSEEF TNEFINSIRY DEGTSFKTTY RNVDILLIDD IQFLSGKEAT 250 260 270 280 290 300 QEEFFHTFNA LHNHNKQVVI TSDLPPKQLS GFEERMRSRF EWGLLTDVQP PELETRIAIL 310 320 330 340 350 360 RKKAIGEGLH APDDVLEYIA SKISTNIREL EGALIRVTAF ASLNRQSVDV GLTETVLKDL 370 380 390 400 410 420 ITDNGDQQIT AATILGQTSA YFKLSLDELR SKSRTRTLVN ARQIAMYLCR ELTDLSLPKI 430 440 450 460 GQELGGRDHT TVIHADRKIR ELMAERRTIF NQVTELTNLI RQQQREG

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY21761.1.
RefSeq	YP_001623175.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WR29.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WR29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5824601.
GenomeReviews	Gene locus RSal33209_0001 in contig CP000910_GR.
KEGG	rsa:RSal33209_0001.
PATRIC	23073116. VBIRenSal21953_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG695666.
OMA	CHTLNAL.
ProtClustDB	PRK00149.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_0001-MONOMER.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9WR29_RENSM

Accession

Primary (citable) accession number: A9WR29

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)