A9WQR6 (MQO_RENSM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	RSal33209_1912

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP]

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	495 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 495	495	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000078035

Sequences

	Sequence		Length	Mass (Da)
	A9WQR6 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 8154744C10162717	FASTA	495	53,745
	10 20 30 40 50 60 MTFISQTKEA DVVFIGGGIM SATLGAMIRQ IQPDWSVVVF EQLNELGQES SGPWNNAGTG 70 80 90 100 110 120 HSALCELNYT PAAKDGSVEA SKALAINEQF QLSRQFWSHM VDKQFIGSPK NFINTVPHMS 130 140 150 160 170 180 FVMGKDHTDF LRTRYEALKP NPLFSSMEFS SDPSQIEKWA PLVMKGRSGN GPVAATRAAE 190 200 210 220 230 240 GTDVDFGQLT KELVGYLGNN DAEINYGTTV TDIQRGTDKR WHLKLKHKAS GEHGAIKARF 250 260 270 280 290 300 VFIGSGGGAL HLLQRSGIPQ GKGYGGFPVS GQFFRCTNEE IAAQHSAKVY GQASVGAPPM 310 320 330 340 350 360 SVPHLDTRYV GGKKSLLFGP YAGFSTNFLK SGSLWDLPLS IRPSNIYPMA AAGLHNLGLT 370 380 390 400 410 420 KYLVSEVLKT RSSKVTAMQE YFPQADGNDW ELITAGQRVQ IMKKDRKQGG ILQFGTEVIT 430 440 450 460 470 480 SSDGSIGALL GASPGASTAV PIMLELLQRC FPREFKLQWQ DQLKDMIPTL GTKLNDNAEL 490 AAATMARTAA TLQLD

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY23645.1.
RefSeq	YP_001625059.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WQR6.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WQR6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5822620.
GenomeReviews	Gene locus RSal33209_1912 in contig CP000910_GR.
KEGG	rsa:RSal33209_1912.
PATRIC	23077159. VBIRenSal21953_1996.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_1912-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_RENSM

Accession

Primary (citable) accession number: A9WQR6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program