A9WPH8 (A9WPH8_RENSM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Delta-aminolevulinic acid dehydratase EMBL ABY22963.1
EC=4.2.1.24 EMBL ABY22963.1

Gene names

Ordered Locus Names:

RSal33209_1225

Organism

Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) [Complete proteome] [HAMAP] EMBL ABY22963.1

Taxonomic identifier

288705 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Renibacterium

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5
Molecular function	Lyase EMBL ABY22963.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	197	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	249	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	234	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	207	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	218	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	275	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	314	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	A9WPH8 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 0E09B4B6E5C9BC8C	FASTA	326	35,461
	10 20 30 40 50 60 MSFPTQRPRR LRSTPAMRRL VAEYRVHRAD LILPVFVKES LREPKPIPSM PGVVQHSSDS 70 80 90 100 110 120 LRRAAAEAAE KGLGGIMLFG IPAERDSMGS GSIAEQGILN RSIREVRAEV GDELVVMSDL 130 140 150 160 170 180 CLDEFTDHGH CGVLDEQGRV DNDATLEIYA QMAVAQANAG AHLLGPSGMM DGQIAVIRQA 190 200 210 220 230 240 LDEAGYQETG VLAYSAKYGS AFYGPFRDAV DSALQGDRRT YQMDASNRRE ALLEVELDLQ 250 260 270 280 290 300 EGADMVMVKP AMSYLDILAD VAAISPVPVA AYQISGEYAM IEAAAANGWI DRRAAIEESV 310 320 LSIKRAGADS ILTYWATELA DWLAER

References

[1]

"Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor." Wiens G.D., Rockey D.D., Wu Z., Chang J., Levy R., Crane S., Chen D.S., Capri G.R., Burnett J.R., Sudheesh P.S., Schipma M.J., Burd H., Bhattacharyya A., Rhodes L.D., Kaul R., Strom M.S. J. Bacteriol. 190:6970-6982(2008) [PubMed: 18723615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000910 Genomic DNA. Translation: ABY22963.1.
RefSeq	YP_001624377.1. NC_010168.1.
3D structure databases
ProteinModelPortal	A9WPH8.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WPH8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5822480.
GenomeReviews	Gene locus RSal33209_1225 in contig CP000910_GR.
KEGG	rsa:RSal33209_1225.
PATRIC	23075691. VBIRenSal21953_1266.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285270.
OMA	FTSHGHD.
ProtClustDB	PRK09283.
Enzyme and pathway databases
BioCyc	RSAL288705:RSAL33209_1225-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A9WPH8_RENSM

Accession

Primary (citable) accession number: A9WPH8

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)