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A9WKE4 (PGK_CHLAA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Caur_2821
OrganismChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [Reference proteome] [HAMAP]
Taxonomic identifier324602 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeChloroflexus

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000076582

Regions

Nucleotide binding355 – 3584ATP By similarity
Region21 – 233Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1211Substrate By similarity
Binding site1541Substrate By similarity
Binding site2041ATP By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A9WKE4 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: DCE0DC93708E378C

FASTA40042,310
        10         20         30         40         50         60 
MNKKTIRDVD WAGKRALVRV DFNVPLDDQG QITDDTRIRA ALPTIRYLLE HGASVVLMSH 

        70         80         90        100        110        120 
LGRPKGKPNP KYSLRPVVER LFELLPEAKE VKKTEAITGP AAEAAVAMLK PGQVLVLENT 

       130        140        150        160        170        180 
RFDPREEPND PAMAAELAKL GDVFVNDAFG TAHRANASTE GVAHYLPAVA GFLMEKELTY 

       190        200        210        220        230        240 
IGGALNNPQR PFVTVIGGAK ISDKIGVIEN LLGKVDALLI GGGMANTFLL AKGLNVGDSL 

       250        260        270        280        290        300 
VEPDSVPVAQ QLMARAEERG ARLLLPVDVV IADAFSADAQ RQVVDVSDIP AGWRVLDIGP 

       310        320        330        340        350        360 
KTIERYSAEI RAARTVIWNG PMGVFELEPF AVGTRAIAQA MAEAAANGAI TIVGGGDSVA 

       370        380        390        400 
AVEQAGLADK MSHVSTGGGA SLELLEGRVL PGVAALQDAE 

« Hide

References

[1]"Complete genome sequence of the filamentous anoxygenic phototrophic bacterium Chloroflexus aurantiacus."
Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J., Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W., Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.
BMC Genomics 12:334-334(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29366 / DSM 635 / J-10-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000909 Genomic DNA. Translation: ABY36022.1.
RefSeqYP_001636411.1. NC_010175.1.

3D structure databases

ProteinModelPortalA9WKE4.
SMRA9WKE4. Positions 1-398.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING324602.Caur_2821.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY36022; ABY36022; Caur_2821.
GeneID5827292.
KEGGcau:Caur_2821.
PATRIC21416865. VBIChlAur28763_3176.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAGLDCGEK.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycCAUR324602:GIXU-2867-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_CHLAA
AccessionPrimary (citable) accession number: A9WKE4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways