A9WJC5 (A9WJC5_CHLAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 1 HAMAP MF_01023

Gene names

Name:	hisC1 HAMAP MF_01023
Ordered Locus Names:	Caur_1172

Organism

Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) EMBL ABY34402.1

Taxonomic identifier

324602 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023
Ligand	Pyridoxal phosphate HAMAP MF_01023
Molecular function	Aminotransferase HAMAP MF_01023 EMBL ABY34402.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	219	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	A9WJC5 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: F875E33571408D05	FASTA	366	39,230
	10 20 30 40 50 60 MPIRKKAFLQ ALSPTPPPRR SSTGVVVARL SANENPLGPS PRAMAAVQEA LSTIHRYPDA 70 80 90 100 110 120 SGVALKEALA ARVDLHPDQV MLGNGSDELI MLICHAMLGE GDEAVLAQGS FISYARRIQA 130 140 150 160 170 180 QGAIARQVPL REMTHDLPAM AAAITPQTRL IFVCNPNNPT GTTVGAAELM AFLEQVPPDV 190 200 210 220 230 240 LVVVDEAYLE FVTRPDFPDL LPLLRDGRDN LLIVRTFAKI HGLAGLRLGY AFGNADLIAY 250 260 270 280 290 300 LERARPVFNV NVLAQIAGLA ALDDVDHLER SLAHAAASRA FLTDHLRAMG MTVIPGETNF 310 320 330 340 350 360 VVAAIADDTA VAAELARRGV LVTPLSGWGL PGWMRISFGT AEENRVFIEV LRNLMSKGTV ATATIS

References

[1]

"Complete sequence of Chloroflexus aurantiacus J-10-fl." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Pierson B.K., Blankenship R.E., Richardson P. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29366 / DSM 635 / J-10-fl.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000909 Genomic DNA. Translation: ABY34402.1.
RefSeq	YP_001634791.1. NC_010175.1.
3D structure databases
ProteinModelPortal	A9WJC5.
ModBase	Search...
Protein-protein interaction databases
STRING	A9WJC5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5825974.
GenomeReviews	Gene locus Caur_1172 in contig CP000909_GR.
KEGG	cau:Caur_1172.
PATRIC	21413141. VBIChlAur28763_1340.
Phylogenomic databases
HOGENOM	HBG646350.
OMA	SSNEVAF.
PhylomeDB	A9WJC5.
ProtClustDB	CLSK2476825.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A9WJC5_CHLAA

Accession

Primary (citable) accession number: A9WJC5

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)