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A9WIS7 (GSA_CHLAA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase

Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:hemL
Ordered Locus Names:Caur_2598
OrganismChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) [Reference proteome] [HAMAP]
Taxonomic identifier324602 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeChloroflexus

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 443443Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375
PRO_1000079915

Amino acid modifications

Modified residue2721N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
A9WIS7 [UniParc].

Last modified February 5, 2008. Version 1.
Checksum: 963BA7CDC5AD6512

FASTA44346,746
        10         20         30         40         50         60 
MSVVTERYSR SQADYAAARE VIPGGVNSPV RAFRGVGGIP IFFERGQGAY VWDVDGNRYI 

        70         80         90        100        110        120 
DYVLSWGPLL LGHAHPAVVE AITLQAQRGT SFGAPTELET ELARLVIELV PSIEQIRFVN 

       130        140        150        160        170        180 
SGTEATMSAL RLARAATGRR LIVKFNGCYH GHADMLLVQA GSGVATLGLP DSPGVPPSVA 

       190        200        210        220        230        240 
AETITIEYND LDAAAALFAN RGAEIAAVIV EPIAANMGFV LPKPGFLSGL RELTQTHGAI 

       250        260        270        280        290        300 
FILDEVMTGF RVAAGGAQAL WGLDPDLTCL GKVIGGGLPV GAYAGKRQLM QLVAPAGPMY 

       310        320        330        340        350        360 
QAGTLSGNPL AMTAGLTTLR TAFGGDAGAF QQAVTRTARL ADGLRMLGER YRIPVQVGNV 

       370        380        390        400        410        420 
GTMFGCYFLR QEGSQITSYA EAKAYADSQR YARFFWAMAD QGIYLAPSQF EAGFLSTAHS 

       430        440 
DADIDETLAA AEVAFAGLVS SAE 

« Hide

References

[1]"Complete genome sequence of the filamentous anoxygenic phototrophic bacterium Chloroflexus aurantiacus."
Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J., Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W., Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.
BMC Genomics 12:334-334(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29366 / DSM 635 / J-10-fl.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000909 Genomic DNA. Translation: ABY35804.1.
RefSeqYP_001636193.1. NC_010175.1.

3D structure databases

ProteinModelPortalA9WIS7.
SMRA9WIS7. Positions 9-434.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING324602.Caur_2598.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABY35804; ABY35804; Caur_2598.
GeneID5827067.
KEGGcau:Caur_2598.
PATRIC21416359. VBIChlAur28763_2926.

Phylogenomic databases

eggNOGCOG0001.
HOGENOMHOG000020210.
KOK01845.
OMACSWGPLI.
OrthoDBEOG6QVRHN.
ProtClustDBPRK00062.

Enzyme and pathway databases

BioCycCAUR324602:GIXU-2642-MONOMER.
UniPathwayUPA00251; UER00317.
UPA00668.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPMF_00375. HemL_aminotrans_3.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_CHLAA
AccessionPrimary (citable) accession number: A9WIS7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 5, 2008
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways