Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A9WHH4

- TRMB_CHLAA

UniProt

A9WHH4 - TRMB_CHLAA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei57 – 571S-adenosyl-L-methionineUniRule annotation
Binding sitei82 – 821S-adenosyl-L-methionineUniRule annotation
Binding sitei109 – 1091S-adenosyl-L-methionineUniRule annotation
Binding sitei167 – 1671SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCAUR324602:GIXU-3150-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:Caur_3101
OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifieri324602 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
ProteomesiUP000002008: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 224224tRNA (guanine-N(7)-)-methyltransferasePRO_0000387942Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi324602.Caur_3101.

Structurei

3D structure databases

ProteinModelPortaliA9WHH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000033410.
InParanoidiA9WHH4.
KOiK03439.
OMAiRLVNREF.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A9WHH4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGRGRYPARL YVTAPPPEIA ARYYRSWPAK ELYHTPEHFP PVSAEGLFGY
60 70 80 90 100
NAPLTLEFGC ATGEYLCALA AAQPSSCFVG IDIVAKPLYR AVERAVAGNL
110 120 130 140 150
SNILFIHADA RLIYQRIPTA ALHSIILHFP PPLLRNRQRN QLLVSPQLLE
160 170 180 190 200
CAARTLVPGG YLSFLTDHPA LFALMQELLP AFPALRATPA SVEELAVFES
210 220
HYHRRWAARG RTISGLRIER VMED
Length:224
Mass (Da):24,960
Last modified:February 5, 2008 - v1
Checksum:iA30622F44EFDBF20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000909 Genomic DNA. Translation: ABY36300.1.
RefSeqiYP_001636689.1. NC_010175.1.

Genome annotation databases

EnsemblBacteriaiABY36300; ABY36300; Caur_3101.
GeneIDi5827575.
KEGGicau:Caur_3101.
PATRICi21417531. VBIChlAur28763_3505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000909 Genomic DNA. Translation: ABY36300.1 .
RefSeqi YP_001636689.1. NC_010175.1.

3D structure databases

ProteinModelPortali A9WHH4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 324602.Caur_3101.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABY36300 ; ABY36300 ; Caur_3101 .
GeneIDi 5827575.
KEGGi cau:Caur_3101.
PATRICi 21417531. VBIChlAur28763_3505.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000033410.
InParanoidi A9WHH4.
KOi K03439.
OMAi RLVNREF.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci CAUR324602:GIXU-3150-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29366 / DSM 635 / J-10-fl.

Entry informationi

Entry nameiTRMB_CHLAA
AccessioniPrimary (citable) accession number: A9WHH4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: February 5, 2008
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3